Abstract
Circulating erythrocytes of mammals are incapable of haemoglobin synthesis. Haemoglobin is produced mainly by erythroblasts and reticulocytes in the bone marrow. In addition, circulating reticulocytes synthesize some haemoglobin. The circulating immature erythrocytes of nonmammalian vertebrates actively take up iron and produce haemoglobin. Upon maturation haemoglobin synthesis slows down. The synthesis of haem and globin chains are independent events. After the synthesis of the haem group and globin chains, they are assembled to form the characteristic quarternary structure of haemoglobin.
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© 1990 Springer-Verlag Berlin Heidelberg
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Nikinmaa, M. (1990). The Biosynthesis and Structure of Haemoglobin. In: Vertebrate Red Blood Cells. Zoophysiology, vol 28. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83909-2_3
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DOI: https://doi.org/10.1007/978-3-642-83909-2_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-83911-5
Online ISBN: 978-3-642-83909-2
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