The amount of oxygen transported by unit volume of blood depends on the partial pressure of oxygen in the blood, on the number of red cells per unit volume, on the amount of functional haemoglobin within the red cells and on the oxygen affinity of haemoglobin. Haemoglobin-oxygen affinity plays a dual role in the transport of oxygen to the tissue. Haemoglobin must be able to bind oxygen effectively in the capillaries of the gas exchange organs, and unload oxygen at high partial pressures in order to maintain a large diffusion gradient for oxygen between the blood in tissue capillaries and the oxygen-consuming structures.
KeywordsOxygen Tension Oxygen Affinity Organic Phosphate Bohr Effect Root Effect
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