Summary
Two survey articles of reports on the association of passive smoking with lung cancer have recently appeared, and also a comprehensive report on the subject of environmental tobacco smoke by a committee of the National Research Council of the United States. The observed excess over a relative risk of unity cannot be explained by chance. Nor can it be fully accounted for by a particular source of bias, the false claims of being non-smokers by individuals who were active or ex-smokers. That possible source of bias leads, in one summary survey, to reducing a relative risk of 1.35 to 1.30, but from 1.34 to 1.15 in the National Research Council report. The latter report suggests that statistical significance would no longer obtain, perhaps, particularly, because of other possible biases. However, to get an estimate of the correct relative risk due to passive smoking, allowance has to be made for actual exposure to passive smoking of those not exposed at home. Thus, the 1.30 is adjusted upwards, by 18 in one survey, to 1.53, but by only 8% in the National Research Council report to 1.24. The National Research Council report had given an anticipated relative risk of 1.1 based on dosimetric considerations. But it is suggested here that that could be as low as 1.05, too low to be detected in an epidemiologic investigation — in any case it would be based on hypothetical assumptions.
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© 1990 Springer-Verlag Berlin Heidelberg
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Mantel, N. (1990). What Is the Epidemiologic Evidence for a Passive Smoking— Lung Cancer Association?. In: Kasuga, H. (eds) Indoor Air Quality. International Archives of Occupational and Environmental Health Supplement. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83904-7_40
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DOI: https://doi.org/10.1007/978-3-642-83904-7_40
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