Extracorporeal Oxygen Delivery and Life Support in Neonatal Respiratory Failure
Most of the variables which influence oxygen delivery and oxygen consumption are controlled during extracorporeal circulation, hence it is appropriate to include this topic in the Steglitz Symposium. In fact, extracorporeal circulation is an exercise in applied physiology of oxygen kinetics. Whether in the laboratory or at the bedside the physiologist or physician can address problems which can not be solved in any other way. Prolonged extracorporeal circulation has been described by the acronym ECMO (extracorporeal membrane oxygenation), but this represents only one of the variables. Extracorporeal life support (ECLS) is a better term, describing oxygen exchange, CO2 exchange, perfusion, and temperature control.
KeywordsCatheter Dioxide Ischemia Albumin Europe
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- 2.Gattinoni L, Pesenti A, Pelizzola A et al. (1981) Reversal of terminal acute respiratory failure by low frequency positive pressure ventilation with extracorporeal removal of CO2 (LFPPV-ECCO2R). ASAIO Trans 27:289–293Google Scholar
- 3.Cilley RE, Polley TZ, Zwischenberger JB, Toomasian JM, Bartlett RH (1989) Independent measurement of oxygen consumption and oxygen delivery. J Surg Res (in press)Google Scholar
- 5.Ladowski JS, Borovetz HS, Brant AM, Griffith BP, Hardesty RL (1984) Flow characteristics of Kolobow system for extracorporeal CO2 removal (ECCO2-R). ASAIO Trans 30:635Google Scholar
- 6.Neonatal ECMO Registry (1989) Ann Arbor, Michigan, January 1989Google Scholar
- 12.Towne BH, Lott IT, Hicks DA et al. (1985) Long-term follow-up of infants and children treated with extracorporeal membrane oxygenation (ECMO). A preliminary report. J Pediatr Surg 20:410–414Google Scholar
- 15.Schumacher RE, Barks JDE, Johnston MV et al. (1988) Right-sided brain lesions following ECMO. Pediatr 82(2):155–161Google Scholar
- 16.Pearson GD, Short BL (1989) An economic analysis of extracorporeal membrane oxygenation. (in press)Google Scholar
- 17.Voorhies TM, Tardo CI, Starrett AL et al. (1985) Evaluation of the cerebral circulation in neonates following extracorporeal membrane oxygenation. Ann Neurol 18:380Google Scholar
- 19.Kolobow T, Moretti MP, Mascheroni D et al. (1983) Experimental meconium aspiration syndrome in the preterm fetal lamb: successful treatment using the extracorporeal artificial lung. ASAIO Trans 29:221–226Google Scholar
- 20.Durandy Y, Batisse A, Chevalier JY (1988) A new extracorporeal respiratory assist device: initial clinical experience in paediatric patients. Intensive Care Med [Suppl]:268Google Scholar
- 22.Zwischenberger JB, Toomasian JM, Drake K, Andrews AF, Kolobow T, Bartlett RH (1985) Total respiratory support with single cannula venovenous ECMO: dou ble lumen continuous flow vs single lumen tidal flow. ASAIO Trans 31:610–615Google Scholar
- 27.Bindslav L (1988) Adult ECMO performed with surface-heparinized equipment. ASAIO Trans 34:1009–1013Google Scholar