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Contributions of Nuclear Endocrinology to the Diagnosis of Adrenal Tumors

  • Conference paper
Hormone-Related Malignant Tumors

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 118))

Abstract

The scintigraphic evaluation of the adrenal cortex with [131I] 6β-iodomethylnorcholesterol (NP-59) and the sympathomedullary system with [131I]- or [123I]-metaiodobenzylguanidine (MIBG) provides a unique means of depicting the in vivo functional status of these tissues. This functional depiction is complementary to the high-resolution anatomical studies such as computed tomography (CT), ultrasound and magnetic resonance imaging (MRI; Shapiro et al. 1987; Thrall et al. 1978; McEwan et al. 1985). A fundamental principle is that localizing procedures should be performed only when clinical suspicion has led to the performance of appropriate biochemical testing, the results of which support the diagnosis of an endocrine hypersecretory state.

Supported by grants NCI (CA-09015), NIAMDD (R01-AM 21477RAD), GCRC (HEW3M01-RR-0042-21CLR), NIH(R01-CA-43300), the Veterans Administration Research Service, and the Nuclear Medicine Research Fund.

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Authors and Affiliations

  1. Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, MI, 48109, USA

    B. Shapiro, L. M. Fig, M. D. Gross & F. Khafagi

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  2. L. M. Fig
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  3. M. D. Gross
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Editors and Affiliations

  1. Frauenklinik, Medizinische Einrichtungen, Universität Düsseldorf, Moorenstraße 5, 4000, Düsseldorf, Germany

    Lutwin Beck

  2. Gerhard Domagk-Institut für Pathologie, Westfälische Wilhelms-Universität Münster, Domagkstraße 17, 4400, Münster, Germany

    Ekkehard Grundmann

  3. Urologische Klinik, Universität Düsseldorf, Moorenstraße 5, 4000, Düsseldorf, Germany

    Rolf Ackermann

  4. Chirurgische Klinik und Poliklinik I, Universität Düsseldorf, Moorenstraße 5, 4000, Düsseldorf, Germany

    Hans-Dietrich Röher

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Shapiro, B., Fig, L.M., Gross, M.D., Khafagi, F. (1990). Contributions of Nuclear Endocrinology to the Diagnosis of Adrenal Tumors. In: Beck, L., Grundmann, E., Ackermann, R., Röher, HD. (eds) Hormone-Related Malignant Tumors. Recent Results in Cancer Research, vol 118. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83816-3_12

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  • DOI: https://doi.org/10.1007/978-3-642-83816-3_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83818-7

  • Online ISBN: 978-3-642-83816-3

  • eBook Packages: Springer Book Archive

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