The Leukocyte Adhesion Deficiency
Impaired chemotaxis of phagocytic cells has been observed in a group of children who were suffering from recurrent bacterial infections (Anderson et al. 1987; Fischer et al. 1988). It has been later recognized that a membrane glycoprotein was missing on patients leukocytes. This defect was identified as a lack of the leukocyte adhesion molecules LFA-1, Mac-1 and pl50,95 (Springer et al. 1984).
KeywordsMigration Interferon Fibrinogen Noma Meijer
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