The Leukocyte Adhesion Deficiency

  • A. Fischer
  • B. Lisowska-Grospierre
  • F. Le Deist
  • M. T. Dimanche
  • F. Mazerolles
  • P. H. Trung
Conference paper


Impaired chemotaxis of phagocytic cells has been observed in a group of children who were suffering from recurrent bacterial infections (Anderson et al. 1987; Fischer et al. 1988). It has been later recognized that a membrane glycoprotein was missing on patients leukocytes. This defect was identified as a lack of the leukocyte adhesion molecules LFA-1, Mac-1 and pl50,95 (Springer et al. 1984).


None None Natural Killer Activity Subunit mRNA Recurrent Bacterial Infection Leukocyte Integrins 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • A. Fischer
  • B. Lisowska-Grospierre
  • F. Le Deist
  • M. T. Dimanche
  • F. Mazerolles
  • P. H. Trung

There are no affiliations available

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