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Prospective Study of Colonization, Infection and Mortality Rates during Conventional Therapy

  • H. Wiedeck
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 7)

Abstract

During August 1986-January 1987 we evaluated all ICU patients who were expected to be ventilated for more than 4 days, excluding any with pneumonia on admission to the ICU. The 83 patients studied included cases of trauma, abdominal and thoracic surgery, peritonitis, cardiopulmonary insufficiency and vascular diseases; patients were mechanically ventilated for 8–14 days. Gastrointestinal surgical patients were given systemic prophylaxis with mezlocillin (3 × 4 g) and metronidazole (2 × 0.5 g) for 24 h; trauma patients with open fractures were given prophylactic cefazolin (3 × 2 g) and netilmicin (3 × 150 mg) for 48 h. Diffuse peritonitis was treated with mezlocillin (3 × 4 g), metronidazole (2 × 0.5 g) and netilmicin (3 × 150 mg). Antibiotic therapy for respiratory tract infections was based on susceptibility tests. Pharyngeal and rectal swabs, tracheal aspirates, urine cultures, and — if necessary — swabs from wounds and drains were taken immediately after admission to the ICU and routinely three times a week thereafter. Only pirenzepine was used for stress ulcer prophylaxis; antacids and H2-blockers were not used.

Keywords

Respiratory Tract Infection Trauma Patient Surgical Patient Susceptibility Test Open Fracture 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • H. Wiedeck

There are no affiliations available

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