Abstract
The role of erythropoietin in the regulation of erythropoiesis is well documented. Conclusive evidence exists that the kidney is a major source of erythropoietin. Not surprisingly, anemia or secondary erythrocytosis accompanies renal diseases. Anemia is a regular feature of chronic renal failure and its primary cause is decreased erythropoietin production, while secondary erythrocytosis is caused by increased erythropoietin.
This study was supported by a grant from the Serbian Research Foundation. The research was also supported in part by a grant from the National Heart, Lung and Blood Institute (NHLBI-22469), USA, and conducted at the Lawrence Berkeley Laboratory (Department of Energy contract DE-AC03-76SF00098 to the University of California).
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Pavlović-Kentera, V., Clemons, G.K., Djukanović, L. (1989). Pathophysiology of Erythropoiesis in Renal Diseases. In: Jelkmann, W., Gross, A.J. (eds) Erythropoietin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83745-6_9
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