Abstract
Arachidonic acid (AA) and its metabolites are intimately involved in the pathogenesis of the adult respiratory distress syndrome (ARDS) [1]. When platelets are stimulated, the AA cascade is triggered leading to the synthesis of thromboxane A2 (TxA2). TxA2 is a potent stimulator of platelet aggregation, broncho- and vasoconstrictor, and mediator of inflammation. The trapping of platelets in the pulmonary microvessels and the release of TxA2 can be regarded as one of the major events in the pathogenesis of ARDS [1, 2].
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References
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© 1989 Springer-Verlag Berlin Heidelberg
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Leithner, C., Frass, M., Traindl, O. (1989). PGE1 for Prevention and Treatment of ARDS After Surgery. In: Vincent, J.L. (eds) Update 1989. Update in Intensive Care and Emergency Medicine, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83737-1_11
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DOI: https://doi.org/10.1007/978-3-642-83737-1_11
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-50879-3
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