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Bone Transplantation pp 7–19Cite as

Early Research on Bone Transplantation

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Abstract

The reconstruction of large skeletal defects presents a challenging problem to the orthopedic community. The treatment of these defects has evolved significantly during the past two decades [14]. The recent, increased demand for bone grafts for reconstruction in limb salvage surgery for bone tumors and for reconstruction of failed arthroplasties has renewed interest in bone graft surgery. The types of grafts clinically available for use are nonvascularized auto- and allografts. Allografts (formerly homografts) are taken from a different individual of the same species, whereas autografts are harvested from the same individual. Xenografts (formerly heterografts) are grafts from a different species and are rarely used [58, 59]. Cellular elements in allografts are dead, due to processes that are used to diminish the immune response [50, 98]. Fairly convincing data support the concept that only a few cells on the surface of autografts survive, most undergoing necrosis [37, 82, 87].

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References

  1. Abbott LC, Schottsteadt ER, de Saunders JB, Bost FC (1947) The evaluation of cortical and cancellous bone grafting material. A clinical and expermental study. J Bone Joint Surg [Am] 29A: 381

    Google Scholar 

  2. Aho AJ (1973) Allogenic joint transplantation in the dog. Ann Chir Gynaecol Fenniae 62: 226

    CAS  Google Scholar 

  3. Aho Ai (1985) Half-joint transplantation in human bone tumours. Int Orthop (SICOT) 9: 77

    Article  CAS  Google Scholar 

  4. Albee FH (1915) Bone graft surgery. Saunders, Philadelphia

    Google Scholar 

  5. Allieu Y, Gomis R, Yoshimura M, Dimeglio A, Bonnet F (1981) Congenital pseudarthrosis of the forearm — two cases treated by free vascularized fibular graft. J Hang Surg 6A: 475

    CAS  Google Scholar 

  6. American Replantation Mission to China (1973) Replantation surgery in China. Plast Reconstr Surg 52: 476

    Google Scholar 

  7. Arata MA, Wood MB, Cooney WP (1984) Revascularized segmental diaphyseal bone transfers in the canine. J Reconstr Microsurg 1: 11

    Article  PubMed  CAS  Google Scholar 

  8. Axhausen G (1907) Histologische Untersuchungen bei Knochentransplantationen am Menschen. Dtsch Z Chir 91: 388

    Article  Google Scholar 

  9. Barth A (1893) Über histologische Befunde nach Knochenimplantationen. Arch Klin Chir 46: 409

    Google Scholar 

  10. Bassett CAL (1962) Current concepts of bone formation. J Bone Joint Surg [Am] 44A: 1217

    Google Scholar 

  11. Bassett CAL (1972) Clinical implication of cell function in bone grafting. Clin Orthop 87: 49

    PubMed  CAS  Google Scholar 

  12. Bieber EJ, Wood MB (1986) Bone reconstruction. Clin Plast Surg 13: 645

    PubMed  CAS  Google Scholar 

  13. Biemer E, Stock W (1983) Total thumb reconstruction: one stage thumb reconstruction using an osteo-cutaneous forearm flap. Br J Plast Surg 36: 52

    Article  PubMed  CAS  Google Scholar 

  14. de Boer HH (1988) The history of bone grafts. Clin Orthop 226: 26

    Google Scholar 

  15. de Boer HH (1988) Free vascularized fibular transfer. PhD thesis, University of Leiden

    Google Scholar 

  16. de Boer HH, Verbout AJ, Nielsen HKL, van der Eijken JW (1988) Free vascularized fibular graft for tibial pseudarthrosis in neurofibromatosis. Acta Orthop Scand 59: 425

    Article  PubMed  Google Scholar 

  17. Bonfiglo M, Jeter WS, Smith CL (1955) The immune concept. Its relation to bone transplantation. Ann NY Acad Sci 59: 417

    Google Scholar 

  18. Bos KE (1979) Bone scintigraphy of experimental composite bone grafts revascularized by microvascular anastomoses. Plast Reconstr Surg 64: 353

    Article  PubMed  CAS  Google Scholar 

  19. Bos KE (1980) Transplantation of revascularized autologenous bone, an experimental study. Thesis, University of Amsterdam, 1980

    Google Scholar 

  20. Brooks B, Hudson WA (1920) Studies in bone transplantations. An experimental study of the comparative success of autogenous and homogenous transplants of bone in dogs. Arch Surg 1: 284

    Article  Google Scholar 

  21. Brown JB (1940) Preserved and fresh homotransplants of cartilage. Surg Gynecol Ob-stet 70: 1079

    Google Scholar 

  22. Buncke HJ, Fumas DW, Gordon L, Achauer BM (1977) Free osteocutaneous flap from a rib to the tibia. Plast Reconstr Surg 59: 799

    Article  PubMed  CAS  Google Scholar 

  23. Burchardt H (1983) The biology of bone graft repair. Clin Orthop 174: 28

    PubMed  Google Scholar 

  24. Burwell RG (1963) Studies in the transplantation of bone. The capacity of fresh and treated homografts of bone to evoke transplantation immunity. J Bone Joint Surg [Br] 45B: 386

    Google Scholar 

  25. Campbell CJ (1972) Homotransplantation of a half or whole joint. Clin Orthop 87: 146

    PubMed  CAS  Google Scholar 

  26. Carrel A (1908) Results of the transplantation of blood vessels, organs and limbs. JAMA 51: 1661

    Google Scholar 

  27. Chacha PB (1984) Vascularized pedicular bone grafts. Int Orthop (SICOT) 8: 117

    Article  CAS  Google Scholar 

  28. Chalmers J (1959) Transplantation immunity in bone homografting. J Bone Joint Surg [Br] 41B: 160

    Google Scholar 

  29. Chase SW, Herndon CH (1955) The fate of autogenous and homogenous bonegrafts. J Bone Joint Surg [Am] 37A: 809

    Google Scholar 

  30. Curtis BF (1893) Cases of bone implantation and transplantation for cyst of tibia, osteomyelitis cavities and ununited fractures. Am J Med Sci 106: 30

    Google Scholar 

  31. Cutting CB, McCarthy JG (1983) Comparison of residual osseous mass between vascularized and non vascularized onlay bone transfers. Plast Reconstr Surg 72: 672

    Article  PubMed  CAS  Google Scholar 

  32. Daniel RK (1977) Free rib transfer by microvascular anastomoses. Plast Reconstr Surg 59: 737

    Article  PubMed  CAS  Google Scholar 

  33. Davies JB (1954) The muscle-pedicle bone graft in hip fusion. J Bone Joint Surg [Am] 36A: 790

    Google Scholar 

  34. Doi K, Tominaga S, Shibata T (1977) Bone grafts with microvascular anastomoses of vascular pedicles. J Bone Joint Surg [Am] 59A: 809

    CAS  Google Scholar 

  35. Doppelt SH, Tomford WW, Lucas AD, Mankin HJ (1981) Operational and financial aspects of a hospital bone bank. J Bone Joint Surg [Am] 63A: 244

    Google Scholar 

  36. Enneking WF (1957) Histological investigation of bone transplants in immunologically prepared animals. J Bone Joint Surg [Am] 39A: 597

    Google Scholar 

  37. Enneking WF, Burchardt H, Puhl JJ, Piotrowski G (1975) Physical and biologic aspects of repair in dog cortical bone transplants. J Bone Joint Surg [Am] 57A: 232

    Google Scholar 

  38. Enneking WF, Eady JL, Burchardt H (1980) Autogenous cortical bone grafts in the reconstruction of segmental skeletal defects. J Bone Joint Surg [Am] 62A: 1039

    CAS  Google Scholar 

  39. Friedlaender GE, Mankin HJ (1981) Bone banking: current methods and suggested guidelines. In: Murray D (ed) AAOS instructional course lectures, vol 30. Mosby, St Louis pp

    Google Scholar 

  40. Friedlaender GE, Mankin HJ, Sell KW (1981) Osteochondral allografts. Little, Brown, Boston

    Google Scholar 

  41. Fujimaki A, Yamauchi Y (1983) Vascularized fibular grafting for treatment of aseptic necrosis of the femoral head. Microsurgery 4: 17

    Article  PubMed  CAS  Google Scholar 

  42. Gilbert A (1979) A free transfer of the fibula shaft. Int J Microsurg 2: 100

    Google Scholar 

  43. Gilbert A, Judet H, Judet J, Ayatti A (1986) Microvascular transfer of the fibula for necrosis of the femoral head. Int Orthop (SICOT) 9: 885

    CAS  Google Scholar 

  44. Goldberg VM, Heiple KG (1983) Experimental hemi-joint and whole-joint transplantation. Clin Orthop 174: 43

    PubMed  Google Scholar 

  45. Gross AE, Lavoie MV, McDermatt P, Marks P (1985) The use of allograft bone in revision of total hip arthroplasty. Clin Orthop 197: 115

    PubMed  Google Scholar 

  46. Gross AE, McKee N, Farine I, Czitrom A, Langer F (1984) Reconstruction of skeletal defects following en bloc excision of bone tumours. Current concepts of diagnosis and treatment of bone and soft tissue tumours. Springer, Berlin Heidelberg New York, pp 163

    Google Scholar 

  47. Groves EWH (1917) Methods and results of transplantation of bone repair of defects caused by injury or disease. Br J Surg 5: 185

    Article  Google Scholar 

  48. Hagerty RF, Braid HL, Bonner WM Jr, Hennigar GR, Lee WH Jr (1967) Viable and nonviable human cartilage homografts. Surg Gynecol Obstet 125: 485

    PubMed  CAS  Google Scholar 

  49. Havers C (1691) Osteologia nova, or some new observations of the bones. S Smith, London

    Google Scholar 

  50. Heiple KG, Chase SW, Herndon CH (1963) A comparative study of the healing process following different types of bone transplantation. J Bone Joint Surg [Am] 45A: 1593

    CAS  Google Scholar 

  51. de Heyde A (1684) Anatomia Mytuli, Subjecta centuria observatorium. Janssonio Waesbergios, Amsterdam

    Google Scholar 

  52. Hubhard LF, Herndon JH, Buonanno AR (1985) Free vascularized fibula transfer for stabilization of the thoracolumbar spine. Spine 10: 891

    Article  Google Scholar 

  53. Huntington TW (1905) Case of bone transference. Use of a segment of fibula to supply a defect in the tibia. Ann Surg 41: 249

    Article  PubMed  CAS  Google Scholar 

  54. Inclan A (1942) The use of preserved bone graft in orthopaedic surgery. J Bone Joint Surg [Am] 24A: 81

    Google Scholar 

  55. Jacobson JH, Suarez EL (1960) Microsurgery in small anastomoses of small vessels. Surg Forum 11: 243

    Google Scholar 

  56. Judet H, Gilbert A, Judet J (1981) Essai de revascularisation de la tête fémorale dans les nécroses primitives et post-traumatiques. Rev Chir Orthop 67: 261

    PubMed  CAS  Google Scholar 

  57. Jupiter JB, Bour CJ, May JW (1987) The reconstruction of defects in the femoral shaft with vascularized transfers of fibular bone. J Bone Joint Surg [Am] 69A: 365

    CAS  Google Scholar 

  58. Kingma JJ (1960) Results of transplantation with preserved calf bone. Arch Chir Neerl 12: 221

    PubMed  CAS  Google Scholar 

  59. Kingma MJ (1967) Deep frozen calf bone. In: Delchel MJ (ed) Dixième congres de la Société Internationale de Chirurgie Orthopédique et la Traumatologie. Les publications Acta Medica Bruxelles, Paris, p 666

    Google Scholar 

  60. Lacroix P (1947) Organizers and the growth of bone. J Bone Joint Surg [Am] 29A: 292

    CAS  Google Scholar 

  61. Langer F, Czitrom AA, Pritzker KP, Gross AE (1975) The immunogenicity of fresh frozen allogenic bone. J Bone Joint Surg [Am] 57A: 216

    CAS  Google Scholar 

  62. Langer F, Gross AE (1974) Immunogenicity of allograft articular cartilage. J Bone Joint Surg [Am] 56A: 297

    CAS  Google Scholar 

  63. van Leeuwenhoek A (1674) Microscopical observations about blood, milk, bones, the brain, spittle, cuticula, sweat, fat and tears. Philos Trans R Soc Lond 9: 125

    Google Scholar 

  64. Levander’G (1934) On the formation of new bone in bone transplantation. Acta Chir Scand 74: 425

    Google Scholar 

  65. Lexer E (1908) Über Gelenktransplantation. Med Klin 4: 815

    Google Scholar 

  66. Lexer E (1925) Jahre Transplantationsforschung in der Chirurgie. Arch Chir 138:251

    Google Scholar 

  67. Lovie MJ, Duncan GM, Glasson DW (1984) The ulnar artery forearm flap. Br J Plast Surg 37: 486

    Article  PubMed  CAS  Google Scholar 

  68. Macewen W (1881) Observations concerning transplantation on bone. Proc R Soc Lond 32: 232

    Article  Google Scholar 

  69. Mankin HJ, Doppelt SH, Tomford WW (1983) Clinical experience with allograft implantation. The first ten years. Clin Orthop 174: 69

    Google Scholar 

  70. McKnee DM (1978) Microvascular bone transplantation. Clin Plast Surg 5: 283–292

    Google Scholar 

  71. Meals RA, Lesavoy MA (1987) Vascularized free radius transfer for clavicle reconstruction concurrent with below elbow amputation. J Hand Surg [Am] 12: 673

    CAS  Google Scholar 

  72. van Meekeren J (1668) Heel-en geneeskonstige aanmerkingen. Commelijn, Amsterdam

    Google Scholar 

  73. Mnaymneh W, Malinin T, Head W, Bora F, Burkhalter W, Ballard A, Zych G, Reyes F (1986) Massive osseous and osteoarticular allograft in nontumorous disorders. Contemp Orthop 13: 13

    Google Scholar 

  74. Mnaymneh W, Malinin T, Makley T, Dick H (1985) Massive osteoarticular allografts in reconstruction of extremities following resection of tumors not requiring chemotherapy and radiation. Clin Orthop 197: 76

    PubMed  Google Scholar 

  75. O’Brien B MC (1979) Microvascular osteocutaneous transfer using the groin flap and iliac crest and the dorsalis pedis flap and second metatarsal. Br J Plast Surg 32: 188

    PubMed  Google Scholar 

  76. Olerud S, Hendriksson T, Engkvist O (1983) A free vascularized fibular graft in lengthening of the humerus with the Wagner apparatus. J Bone Joint Surg [Am] 65A: 110

    Google Scholar 

  77. Oilier L (1867) Traité experimental et clinique de la régénération des os. Victor Mason et Fils, Paris

    Google Scholar 

  78. Östrup LT, Frederickson JM (1974) Distant transfer of a free living bone graft by microvascular anastomoses. An experimental study. Plast Reconstr Surg 54: 274

    Google Scholar 

  79. Pap K, Krompecher S (1961) Arthroplasty of the knee: experimental and clinical experiences. J Bone Joint Surg [Am] 43A: 523

    Google Scholar 

  80. Parrish FF, (1973) Allograft replacement of all or part of the end of a long bone following excision of a tumor. Report of twenty-one cases. J Bone Joint Surg [Am] 55A: 1

    CAS  Google Scholar 

  81. Phelps AM (1891) Transplantation of tissue from lower animals to man. Med Records 39: 221

    Google Scholar 

  82. Phemister DB (1914) The fate of transplanted bone and regenerative power of its various constituents. Surg Gynecol Obstet 19: 303

    Google Scholar 

  83. Pho RWH (1979) Free vascularized fibular transplant for replacement of the lower radius. J Bone Joint Surg [Br] 61B: 362

    Google Scholar 

  84. Pho RW, Levack B, Satku K, Patradul A (1985) Free vascularized fibular graft in the treatment of congenital pseudarthrosis of the tibia. J Bone Joint Surg [Br] 67B: 64

    CAS  Google Scholar 

  85. Ray RD (1972) Vascularization of bone grafts and implants. Clin Orthop 87: 43

    PubMed  CAS  Google Scholar 

  86. Rodrigo JJ, Fuller TC, Mankin HJ (1976) Cytotoxic HLA-antibodies in patients with bone and cartilage allografts. Trans Orthop Res Soc 1: 131

    Google Scholar 

  87. Schenk R, Willinegger H (1964) Histologie der primären Knochenheilung. Langen-becks Arch Klin Chir 308: 440

    Article  CAS  Google Scholar 

  88. Serafin D, Villareal-Rios A, Georgiade N (1977) A rib containing free flap to reconstruct mandibular defects. Br J Plast Surg 30: 263

    Article  PubMed  CAS  Google Scholar 

  89. Siffert RS, Barash ES (1961) Delayed bone transplantation: an experimental study of early host-transplant relationships. J Bone Joint Surg [Am] 43A: 407

    Google Scholar 

  90. Taylor GI (1977) Microvascular free bone transfer. Orthop Clin North Am 8: 425

    PubMed  CAS  Google Scholar 

  91. Taylor GI, Miller GDH, Ham FJ (1975) The free vascularized bone graft. A clinical extension of microvascular techniques. Plast Reconstr Surg 55: 533

    Article  PubMed  CAS  Google Scholar 

  92. Taylor GA (1983) The current status of free vascularized bone grafts. Clin Plast Surg 10: 185

    PubMed  CAS  Google Scholar 

  93. Teissier J, Bonnel F, Allieu Y (1985) Vascularization, cellular behavior and union of vascularized bone grafts: experimental study in the rabbit. Ann Plast Surg 14: 494

    Article  PubMed  CAS  Google Scholar 

  94. Teót L, Bosse JP, Moufarrige R, Papillon J, Beauregard G (1981) The scapula crest pedicle bone graft. Int J Microsurg 3: 257

    Google Scholar 

  95. Tomford WW, Mankin HJ (1983) Investigational approaches to articular cartilage preservation. Clin Orthop 174: 22

    PubMed  Google Scholar 

  96. Tomford WW, Doppelt SH, Mankin HJ, Friedlaender GE (1983) 1983 Bone bank procedures. Clin Orthop 174: 15

    PubMed  Google Scholar 

  97. Tomford WW, Duff GP, Mankin HJ (1985) Experimental freezepreservation of chondrocytes. Clin Orthop 197: 11

    PubMed  Google Scholar 

  98. Turner J, Bassett CAL, Pate JW, Sawyer PN (1955) An experimental comparison of freeze-dried and frozen cortical bone graft healing. J Bone Joint Surg [Am] 37A: 1197

    Google Scholar 

  99. Ueba Y, Fujikawa S (1983) Nine years follow-up of a vascularized fibular graft in neurofibromatosis. A case report an literature review (in Japanese). Orthop Traum Surg 26 (5): 595

    Google Scholar 

  100. Urist MR (1953) The physiological basis of bone graft surgery, with special reference to the theory of induction. Clin Orthop 1: 207

    PubMed  CAS  Google Scholar 

  101. Urist MR (ed) (1980) Fundamental and clinical bone physiology. Lippincott, Philadelphia

    Google Scholar 

  102. Urist MR, Delange RJ, Finerman GA (1983) Bone cell differentiation and growth factors. Science 220: 680

    Article  PubMed  CAS  Google Scholar 

  103. Urist MR, McLean FC (1952) Osteogenic potency and new-bone formation by induction in transplants to the anterior chamber of the eye. J Bone Joint Surg [Am] 34A: 443

    Google Scholar 

  104. Vokov MV, Mamaliev A (1976) Use of allogenous articular bone implants as substitutes for autotransplants in the adult patients. Clin Orthop 144: 192

    Google Scholar 

  105. Von Walter P (1821) Wiedereinheilung der bei der Trapanation ausgebohrten Knochenscheibe. Journal der Chirurgie und Augen-Heilkunde 2: 571

    Google Scholar 

  106. Weiland AJ, Kleinert HE, Kutz JE, Daniel RK (1979) Free vascularized bone grafts in surgery of the upper extremity. J Hand Surg [Am] 4: 129

    CAS  Google Scholar 

  107. Weiland AJ (1984) Vascularized bone transfer. Instr Course Lect 33: 446

    PubMed  CAS  Google Scholar 

  108. Weiland AJ, Daniel RK (1980) Congenital pseudarthrosis of the tibia: treatment with vascularized autogenous fibular grafts. A preliminary report. John Hopkins Med J 147: 89

    CAS  Google Scholar 

  109. Weiland AJ, Daniel RK (1982) Vascularized bone grafts. In: Green DP (ed) Operative hand surgery. Churchill Livingstone, New York, pp 877

    Google Scholar 

  110. Weiland AJ, Morre JR, Daniel RK (1983) Vascularized bone autografts: experience with 41 cases. Clin Orthop 174: 87

    PubMed  Google Scholar 

  111. Wood MB, Cooney WP (1984) Vascularized bone segment transfers for management of chronic osteomyelitis. Orthop Clin North Am 15: 461

    PubMed  CAS  Google Scholar 

  112. Wood MB, Cooney WP, Irons GB (1984) Posttraumatic lower extremity reconstruction by vascularized bone graft transfer. Orthopedics 7: 255

    Google Scholar 

  113. Wood MB, Cooney WP, Irons GB (1985) Skeletal reconstruction by vascularized bone transfer: indications and results. Mayo Clin Proc 60: 729

    PubMed  CAS  Google Scholar 

  114. Wood MB (1987) Upper extremity reconstruction by vascularized bone transfers: results and complications. J Hand Surg [Am] 12A: 422

    CAS  Google Scholar 

  115. Yoshimura M, Shimarrura K, Yoshinobu I, Yarnauchi S, Ueno T (1983) Free vascularized fibular transplant. J Bone Joint Surg [Am] 65A: 1295

    CAS  Google Scholar 

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  1. De Wever Hospital, H. Dunantstraat 5, 6419 PC, Heerlen, The Netherlands

    H. de Boer

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  1. Klinik und Poliklinik für Orthopädische Chirurgie, Inselspital, CH-3010, Bern, Switzerland

    Max Aebi

  2. Departement für Chirurgie, Kantonsspital Basel, Spitalstr. 21, CH-4031, Basel, Switzerland

    Pietro Regazzoni

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de Boer, H. (1989). Early Research on Bone Transplantation. In: Aebi, M., Regazzoni, P. (eds) Bone Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83571-1_2

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