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Cervical Nodal Metastasis from an Unknown Primary Carcinoma

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Radiation Therapy of Head and Neck Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

The diagnostic and therapeutic problems of cervical lymph node metastasis from an occult primary carcinoma are a dilemma for the oncologist. In general, patients who present with metastases and no obvious primary site of origin, have a median survival of three to four months (Holmes and Fouts 1970; Richardson and Parker 1975; Smith et al. 1977). This poor prognosis is not altered by treatment unless a primary site can be identified, or the region that is the most probable primary site can be defined (Nystrom et al. 1977). Autopsy studies of patients who have presented with metastasis from occult primary malignant tumors reveal the site of origin in only 15% of cases.

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References

  • Acquarelli MJ, Matsunaga RS, Cruze K (1961) Metastatic carcinoma of the neck of unknown primary origin. Laryngoscope 71:962–974

    Article  PubMed  CAS  Google Scholar 

  • Barrie JR, Knapper WH, Strong EW (1970) Cervical nodal metastases of unknown origin. Am J Surg 120: 466–470

    Article  PubMed  CAS  Google Scholar 

  • Comess MS, Beahrs OH, Dockerty MB (1957) Cervical metastasis from occult carcinoma. Surg Gyn Obstet 133: 0717

    Google Scholar 

  • Fitzpatrick PJ, Kotalik JF (1974) Cervical metastases from an unknown primary tumor. Radiol 110: 659–663

    CAS  Google Scholar 

  • Fried MP, Diehl WH, Brownson RJ, Sessions DG, Ogura JH (1975) Cervical metastasis from an unknown primary. Ann Otol 84:152–157

    CAS  Google Scholar 

  • Holmes FF, Fouts TL (1970) Metastatic cancer of unknown primary site. Cancer 26: 816–820

    Article  PubMed  CAS  Google Scholar 

  • Jesse RH, Neff LD (1966) Metastatic carcinoma in cervical nodes with an unknown primary lesion. Am J Surg 112: 547–553

    Article  PubMed  CAS  Google Scholar 

  • Jesse RH, Perez CA, Fletcher GH (1973) Cervical lymph node metastasis: Unknown primary cancer. Cancer 31: 854–859

    Article  PubMed  CAS  Google Scholar 

  • Johnson JT, Newman RK (1981) The anatomic location of neck metastasis from occult squamous cell carcinoma. Otolaryngol Head Neck Surg 89: 54–58

    PubMed  CAS  Google Scholar 

  • Jose B, Bosch A, Caldwell WL, Frias Z (1979) Metastasis to neck from unknown primary tumor. ACTA Radiologica 18:161–170

    Article  CAS  Google Scholar 

  • Larkin AJ (1929) Radium in General Practice. Paul B.Hoeber, Inc., New York, p 123

    Google Scholar 

  • Leipzig B, Winter ML, Hokanson JA (1981) Cervical nodal metastases of unknown origin. Laryngoscope 91: 593–598

    Article  PubMed  CAS  Google Scholar 

  • Marchetta FC, Murphy WT, Kovaric JJ (1963) Carcinoma of the neck. Am J Surg 106: 974–979

    Article  PubMed  CAS  Google Scholar 

  • Million RR, Cassisi NJ (1984) The Unknown Primary. In: Management of Head and Neck Cancer. JB Lippincott Co, Philadelphia, pp 231–238

    Google Scholar 

  • Nordstrom DG, Tewfik HH, Latourette HB (1979) Cervical lymph node metastases from an unknown primary. Int J Rad Oncol Biol Phys 5: 3–76

    Google Scholar 

  • Nystrom JS, Weinder JM, Heffelfinger-Juttner J et al. (1977) Metastatic and histologic presentations in unknown primary cancer. Semin Oncol 4 (1): 53–58

    PubMed  CAS  Google Scholar 

  • Pico J, Frias Z, Bosch A (1971) Cervical lymph node metastases from carcinoma of undetermined origin. Am J Roentgenol Radium Ther Nucl Med 91: 95–102

    Google Scholar 

  • Del Regato JA, Spjut HJ, Cox JD (1985) In: Ackerman del Regato (eds) Cancer: Diagnosis, Treatment, and Prognosis, 6th edn. CV Mosby Company, St. Louis, pp 257–272

    Google Scholar 

  • Richardson RG, Parker RG (1975) Metastases from undetected primary cancers - Clinical experience at a radiation oncology center. West J Med 123: 337–339

    PubMed  CAS  Google Scholar 

  • Schwarz D, Hamberger AD, Jesse RH (1981) The management of squamous cell carcinoma in cervical lymph nodes in the clinical absence of a primary lesion by combined surgery and irradiation. Cancer 48:1746–1748

    Article  PubMed  CAS  Google Scholar 

  • Silverman CL, Marks JE, Lee J, Ogura JH (1983) Treatment of epidermoid and undifferentiated carcinomas from occult primaries presenting in cervical lymph nodes. Laryngoscope 93: 645–648

    PubMed  CAS  Google Scholar 

  • Smith PE, Krementz ET, Chapman E (1977) Metastatic cancer with a detectable primary site. J Surg 113: 663–637

    Google Scholar 

  • Wang CC (1983) Management of squamous cell carcinoma in cervical node with “unknown primary”. In: Radiation Therapy for Head and Neck Neoplasms. John Wright, Boston, pp 249–257

    Google Scholar 

  • Yang ZY, Hu YH, Yan JH et al. (1983) Lymph node metastases in the neck from an unknown primary. ACTA Radiol (One) 22:17–22

    Article  CAS  Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Haas, J.S., Cox, J.D. (1989). Cervical Nodal Metastasis from an Unknown Primary Carcinoma. In: Laramore, G.E. (eds) Radiation Therapy of Head and Neck Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83501-8_15

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  • DOI: https://doi.org/10.1007/978-3-642-83501-8_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83503-2

  • Online ISBN: 978-3-642-83501-8

  • eBook Packages: Springer Book Archive

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