Advertisement

HIV-Related Hematological Neoplasias in France

  • J.-M. Andrieu
  • M. Toledano
  • M. Raphael
  • J.-M. Tourani
  • B. Desablens
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 112)

Abstract

In 1981 the unexpected appeareance of opportunistic infections and Kaposi’s sarcoma in homosexual men in the United States marked the beginning of the AIDS epidemic [8]. Shortly thereafter the observation of an increasing number of male homosexual subjects suffering from high-grade non-Hodgkin’s lymphomas [6, 15, 16] resulted in the inclusion of this hematological malignancy in the Centers for Disease Control (CDC) definition of AIDS [4], As early as 1983 the retrovirus responsible for this major immunodeficiency state, now called human immunodeficiency virus (HIV), was discovered [3, 11]. Since then the HIV infection epidemic has been spreading rapidly by means of sexual and intravenous transmission routes in America as well as in Africa and Europe. The discovery of different types of hematological and non hematological malignancies in AIDS patients and HIV-positive subjects led us to create a French register of HIV-related neoplasia. This paper reports the first 68 cases of hematological malignancies identified in this register between 1983 and June 1987.

Keywords

Acquire Immune Deficiency Syndrome Acute Myeloblastic Leukemia Syringe Sharing Acquire Immune Deficiency Syndrome Patient Oral Thrush 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Andrieu JM, Even P, Venet A (1986) AIDS and related syndromes as a viral induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications. AIDS Res 3: 163–174CrossRefGoogle Scholar
  2. 2.
    Baer DM, Anderson ET (1986) Acquired immune deficiency syndrome in homosexual men with Hodgkin’s disease. Am J Med 80: 738–740PubMedCrossRefGoogle Scholar
  3. 3.
    Barré-Sinoussi F, Chermann JC, Rey F et al. (1983) Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 220: 868PubMedCrossRefGoogle Scholar
  4. 4.
    Centers for disease control (1985) Revision of the case definition of acquired immunodeficiency syndrome for national reporting – United States. Ann Intern Med 103: 402–403Google Scholar
  5. 5.
    Di Carlo EF, Ambrson JB, Metroka CE, Ballard P, Moore SA, Mouradian JA (1986) Malignant lymphomas and the acquired immunodeficiency syndrome. Arch Pathol Lab Med 110: 1012–1016PubMedGoogle Scholar
  6. 6.
    Doll DC, List AF (1982) Burkitt’s lymphoma in a homosexual. Lancet 1: 1026–1027PubMedCrossRefGoogle Scholar
  7. 7.
    Doyle TJ, Ventachalam KK, Maeda K, Saedd SM, Tilchen EJ (1983) Hodgkin’s disease in renal transplant recipients. Cancer 51: 245–247PubMedCrossRefGoogle Scholar
  8. 8.
    Gottlieb MS, Schroff R, Schauker HM, Weisman JD, Peng TF, Wolf RA, Saxon A (1981) Pneumocystis carinii pneumonia and mucosal candidiasis in previsusly healthy homosexual men: evidence of a new acquired immunodeficiency. N Eng J Med 305: 1425CrossRefGoogle Scholar
  9. 9.
    Lesser J, Dormont D, Tourani JM, Schwartz O, Fleury H, Neveux Y, Audroin C, Andrieu JM (1987) Particules d’aspect retroviral et activité transcriptase inverse dans des cultures cellulaires dérivées de biopsies ganglionnaires de maladie de Hodgkin. CR Acad Sci (Paris) 305: 295–300Google Scholar
  10. 10.
    Penn I (1983) Lymphomas complicating organ transplantation. Transplant Proc 15: 2790–2797Google Scholar
  11. 11.
    Popovic M, Sarngadharam MG, Read E, Gallo RC (1984) Detection, isolation and continuous production of cytopathic retro-viruses (HTLV III) from patients with AIDS and pre-AIDS. Science 224: 497PubMedCrossRefGoogle Scholar
  12. 12.
    Prior H, Goldberg AF, Conjalka MS, Chapman WE, Tay S, Ames ED (1986) Hodgkin’s disease in homosexual men in AIDS-related phenomenon? Am J Med 81:1085–1088PubMedCrossRefGoogle Scholar
  13. 13.
    Raphael M, Tulliez M, Bellefqin S, Louvel A, Ziza JM, Rozenbaum W (1986) Les lymphomes et le SIDA. Ann Pathol 278: 281–286Google Scholar
  14. 14.
    Unger PD, Strauchen JA (1986) Hodgkin’s disease in AIDS complex patients. Cancer 58: 821–825PubMedCrossRefGoogle Scholar
  15. 15.
    Ziegler JL, Miner CR, Rosenbaum E, Lennette ET, Shillitoe E, Casavour C, Diew WL, Mintz L, Gershow J, Greenspan J, Beckstread J, Yamamoto K (1982) Outbreak of Burkitt’s like lymphoma in homosexual men. Lancet 2: 631–633PubMedCrossRefGoogle Scholar
  16. 16.
    Ziegler JL et al. (1984) Non-Hodgkin’s lymphoma in 90 homosexual men. N Engl J Med 311: 565–569PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1988

Authors and Affiliations

  • J.-M. Andrieu
    • 1
  • M. Toledano
    • 1
  • M. Raphael
    • 1
  • J.-M. Tourani
    • 1
  • B. Desablens
    • 1
  1. 1.Laennec HospitalParisFrance

Personalised recommendations