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Oxygen Sensing in Tissues pp 131–142Cite as

PO2-Induced Changes of Membrane Potential and Tension in Vascular Smooth Musculature

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Abstract

That a decrease in oxygen tension leads to vasodilatation has been known from the literature for a long time. Mechanical measurements demonstrate that hypoxia effects relaxation of vascular strips [8, 9,10, 33], vasodilatation in perfused vessels [5, 6, 7,11], or an increase in blood flow [3, 4,13,17,19, 32]. Electrophysiological investigations during oxygen deficiency, especially intracellular measurements of the membrane potential of vascular smooth muscle cells, do not exist. It has been reported merely that a PO2 decrease in the rat portal vein restricts spontaneous spike discharges and finally causes their complete cessation [16]. Johansson and Somlyo [18] supposed that vasodilatation with hypoxia possibly has an electrophysiological correlate.

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Author information

Authors and Affiliations

  1. Institute of Physiology, Biophysical Research Group, Free University of Berlin, Arnimallee 22, 1000, Berlin 33, Germany

    G. Siegel

  2. Institute of Physiology, University of Bonn, Nußallee 11, 5300, Bonn 1, Germany

    J. Grote

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  1. G. Siegel
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  2. J. Grote
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Editors and Affiliations

  1. Max-Planck-Institut für Systemphysiologie, Rheinlanddamm 201, 4600, Dortmund, Germany

    Helmut Acker

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© 1988 Springer-Verlag Berlin Heidelberg

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Siegel, G., Grote, J. (1988). PO2-Induced Changes of Membrane Potential and Tension in Vascular Smooth Musculature. In: Acker, H. (eds) Oxygen Sensing in Tissues. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83444-8_11

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  • DOI: https://doi.org/10.1007/978-3-642-83444-8_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83446-2

  • Online ISBN: 978-3-642-83444-8

  • eBook Packages: Springer Book Archive

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