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Vasculoconnective Tissue

  • Chapter
Radiopathology of Organs and Tissues

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

The irradiation of tissues with therapeutic doses of x-rays can result in the occurrence of acute, early, and/or late effects. This was initially recognized before the turn of this century. While the acute and early effects of radiation manifest themselves mainly as reactions of the skin, and could be evaluated by visual inspection, the study of the origin of the late effects was, in early times, only possible through histological observations. Surprisingly, since the early observations by Gassmann (1899), Mühsam (1904), and Wolbach (1909) that the blood vessels in irradiated tissues show specific changes, a general consensus seems to have developed among radiation pathologists that blood vessels are sensitive to radiation. Later a hypothesis was proposed that blood vessels were the most likely candidate for dose-limiting late normal responses (Rubin and Casarett 1968).

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Authors and Affiliations

  1. Erasmus University and TNO Radiobiological Institute, Lange Kleiweg 151, P.O. Box 5815, 2280 GJ, Rijswijk, The Netherlands

    H. S. Reinhold M.D.

  2. Research Institute, University of Oxford, Oxford, UK

    J. W. Hopewell Ph.D.

  3. Abteilung für Klinische Physiologie, Universität Ulm, Oberer Eselsberg, 7900, Ulm, Germany

    W. Calvo M.D.

  4. Unité de Radiobiologie, UCL, Brussels, Belgium

    A. Keyeux M.D.

  5. Department de Radiobiologie, CEN/ SCK, Mol, Belgium

    H. Reyners Ph.D.

Authors
  1. H. S. Reinhold M.D.
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  2. J. W. Hopewell Ph.D.
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  3. W. Calvo M.D.
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  4. A. Keyeux M.D.
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  5. H. Reyners Ph.D.
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Editors and Affiliations

  1. Strahlenklinik und Poliklinik, Universitätsklinikum der Gesamthochschule Radiologisches Zentrum, Hufelandstraße 55, W-4300, Essen 1, Germany

    Eberhard Scherer

  2. Institut für Medizinische Strahlenphysik und Strahlenbiologie, Universitätsklinikum der Gesamthochschule, Hufelandstraße 55, W-4300, Essen 1, Germany

    Christian Streffer

  3. Department of Radiation Biology, The Medical College of St. Bartholomew’s Hospital, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott

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© 1991 Springer-Verlag Berlin Heidelberg

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Reinhold, H.S., Hopewell, J.W., Calvo, W., Keyeux, A., Reyners, H. (1991). Vasculoconnective Tissue. In: Scherer, E., Streffer, C., Trott, KR. (eds) Radiopathology of Organs and Tissues. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83416-5_8

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  • DOI: https://doi.org/10.1007/978-3-642-83416-5_8

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