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Paraneoplasias of the Skin

  • G. Niebauer
Conference paper

Abstract

Four processes characterize a malignant neoplasm (Fig. 1).
  1. 1

    Autonomous local cell growth; the tumor cell becomes “correlation deaf”, owing to loss of inhibitory regulators.

     
  2. 2

    Tumor cell spread; penetration and metastases, the main indication of malignancy, caused by a large amount of enzyme activity, prostaglandins, etc.

     
  3. 3

    Pathologic products of metabolism that lead to the production of hormone-type communication.

     
  4. 4

    Host defence mechanisms that come into being mainly by immunologic processes (immune response). This means that a great variety of biochemical, immunologic and other reactions can be shown in every malignant process.

     

Keywords

Bullous Pemphigoid Acanthosis Nigricans Epidermal Proliferation Visceral Malignancy Visceral Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Holzmann H (1971) The relationship between progressive skleroderma, dermatomyositis and cancer. In: Cutane paraneoplastische Syndrome. Fischer, Stuttgart.Google Scholar
  2. 2.
    Kraemer H (1983) Heritable diseases with increased sensitivity to cellular injury. In: Update: dermatology in general medicine. McGraw-Hill, New York.Google Scholar
  3. 3.
    Niebauer G (1983) Paraneoplasien der Haut. In: Dermatologische Onkologie. Urban & Schwarzenberg, München.Google Scholar
  4. 4.
    Niebauer G (1984) Malignom und kutane paraneoplastische Syndrome. Hautarzt 35:602–608.PubMedGoogle Scholar
  5. 5.
    Sönnichsen K, Castanet Ph, Marschall HU (1987) Disseminierte, polymorphe Keratose — Nazarro-Syndrom oder eine neue kutane Paraneoplasie? Akt Dermatol 13:11–16.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • G. Niebauer
    • 1
  1. 1.Department of Dermatology IIUniversity of ViennaViennaAustria

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