Diagnostic Tools, Skin Models

  • P. Stoppie
  • J. Van Wauwe
  • J. Goossens
  • J. van Cutsem
  • M. Borgers
Conference paper

Abstract

The oestrogen stimulated rat vaginal mucosa displays a stratified squamous epithelium with hyperproliferative and hyperkeratinizing features. A rat vaginal mucosa assay has been developed and evaluated as an animal assay for screening potentially useful epithelium affecting drugs.

Keywords

Methotrexate Oestradiol Eosin Paraformaldehyde Glutaraldehyde 

Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • P. Stoppie
    • 1
  • J. Van Wauwe
    • 1
  • J. Goossens
    • 1
  • J. van Cutsem
    • 1
    • 2
  • M. Borgers
    • 1
  1. 1.Dept. of Life SciencesJanssen Research FoundationBeerseBelgium
  2. 2.Dept. of Bacteriology and MycologyJanssen Research FoundationBeerseBelgium

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