• H. Menge
  • M. Gregor
  • G. N. J. Tytgat
  • B. J. Marshall
Conference paper


Börsch: I wish to comment on the problem of a higher positive rate with histology versus with microbiology. We did a formal study in 149 patients comparing biopsy urease tests and histology, and we found the same thing in antral biopsies. We had 48% positive CLO tests and 62% positive histologies by modified Giemsa stain. We considered some of the latter to be false positives. After grading the histologic density of bacteria, we found these “false” positives predominantly to be grade 1 according to Marshall’s grading. So we came to the conclusion that our histological examination gave false positives among the 1 gradings, but we did not have cultures to really rectify this assumption.


False Positive Histological Section Positive Culture Formal Study Histological Specimen 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • H. Menge
    • 1
  • M. Gregor
    • 2
  • G. N. J. Tytgat
    • 3
  • B. J. Marshall
    • 4
  1. 1.Medizinische Klinik II, Krankenanstalten der Stadt RemscheidAkademisches Lehrkrankenhaus der Universität BonnRemscheid 11Germany
  2. 2.Universitätsklinikum Steglitz, Freie Universität BerlinBerlin 45Germany
  3. 3.Department of Gastroentero-Hepatology, Academisch Medisch Centrum Academisch Ziekenhuis bij de Universiteit van AmsterdamAmsterdamThe Netherlands
  4. 4.Division of Gastroenterology, Department of Internal MedicineUniversity of VirginiaCharlottesvilleUSA

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