Approach to Primary Liver Cancer
Primary malignant liver tumor is the most frequent malignoma worldwide. This is due mainly to a high incidence in Asian and African countries. Particularly in these countries, but also in Europe and other continents, most hepatocellular carcinomas are associated with liver cirrhosis. In contrast to this high frequency, therapeutic experience with hepatocellular or cholangiocellular carcinomas has been very limited, at least in Europe. This is not only because of the relative infrequen-cy of this tumor in our countries in comparison with other malignancies ; such tumors were generally diagnosed very late and liver resection therapy was uncommon, particularly in cirrhotic but also in non-cirrhotic patients. Similarly, experience with non-surgical methods is limited. This situation has changed in part within the past few years : ultrasonography and CT scanning, as well as the determination of alpha-fetoprotein, have significantly increased the number of diagnosed tumors and have enabled diagnosis in earlier stages. More specific methods of liver surgery have been developed and, finally, liver grafting was added. Many other approaches for therapy were also instituted. Thus, therapeutic access to a primary liver malignoma became more frequent.
KeywordsHepatocellular Carcinoma Liver Resection Cirrhotic Patient Cirrhotic Liver Liver Grafting
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