Preoperative Radio-Chemotherapy in Anal Carcinoma
Squamous carcinomas of the anus are relatively radiosensitive. Therefore, the combination of radical surgical treatment with radiotherapy seems reasonable. Nigro et al.  added chemotherapy to this two-modality treatment. The rationale of adding cytotoxic medication was to potentiate the radiosensitivity of the tumor cells. After their first extraordinarily satisfying results sphincter-sacrificing operations could be postponed for most of their patients . Meanwhile, several publications have reported excellent remission rates [1–3, 6, 7].
KeywordsAnal Canal Combine Therapy Local Excision Anal Carcinoma Abdominoperineal Excision
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