Preoperative Radio-Chemotherapy in Anal Carcinoma

  • H. Denecke
  • R. Roloff
Conference paper
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 110)


Squamous carcinomas of the anus are relatively radiosensitive. Therefore, the combination of radical surgical treatment with radiotherapy seems reasonable. Nigro et al. [4] added chemotherapy to this two-modality treatment. The rationale of adding cytotoxic medication was to potentiate the radiosensitivity of the tumor cells. After their first extraordinarily satisfying results sphincter-sacrificing operations could be postponed for most of their patients [5]. Meanwhile, several publications have reported excellent remission rates [1–3, 6, 7].


Anal Canal Combine Therapy Local Excision Anal Carcinoma Abdominoperineal Excision 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1988

Authors and Affiliations

  • H. Denecke
    • 1
  • R. Roloff
    • 1
  1. 1.Klinik und Poliklinik für Chirurgie und Radiologie, Klinikum GroßhadernUniversität MünchenMünchen 70Germany

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