Zusammenfassung
Immunsuppressiva haben in den letzten Jahren eine zunehmende Bedeutung in der mehr und mehr therapeutisch ausgerichteten klinischen Neurologie erhalten.
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Literatur
Aimar G, Confavreux C, Ventre JJ, Guillot M, Devic M (1983) Etude de 213 cas de sclerose en plaques traités purl’azathioprine de 1967 à 1982. Rev Neurol 139:509–513
Borel JF (1981) Cyclosporin A -present experimental status. Transplant Proc 13:344–348
Borel JF, Feurer C, Gubler HU, Staehelin H (1976) Biological effects of cyclosporin A: A new antilymphocytic agent. Agents Actions 6/4: 468–475
Borel JF, Ryffel B (1985) The mechanism of action of cyclosporin: A continuing puzzle. In: Schindler R (ed) Cyclosporin in autoimmune diseases. Springer, Berlin Heidelberg New York Tokyo, pp 24–30
Colombani PM, Robb A, Hess AD (1985) Cyclosporine binding to calmodulin: A possible site of action on T lymphocytes. Science 228:337–339
Dommasch D, Depisch R, Pflughaupt W, Kappos L, Krauseneck P (1984) Demonstration of cyclosporin A in the CSF of multiple sclerosis patients. Clin Res Unit MS Ann Rep 2:26
Donatsch P, Abisch E, Homberger M (1981) A radioimmunoassay to measure cyclosporin A in plasma and serum samples. J Immunoassay 2:19–32
Faakerley JK, Webb HE (1985) Cyclosporin, blood-brain-barrier, and multiple sclerosis. Lancet II:889–890
Graffenried B von, Harrison WB (1985) Cyclosporin in autoimmune disease -side effets (with emphasis on venal dysfunction) and recommandations for use. In: Schindler R (ed) Cyclosporin in autoimmune diseases. Springer, Berlin Heidelberg New York Tokyo, pp 59–73
Handschumacher ER, Harding MW, Rice J, Drugge RJ (1984) Cyclophilin: A specific cytosolic binding protein for cyclosporin A. Science 226: 544–547
Kappos L (1983) Selbstbeurteilungsskala für Befindlichkeitsveränderungen bei Multipler Sklerose. Psycho 9:362–363
Kastrukoff LF, Paty DW (1984) A serial study of peripheral blood T lymphocyte subsets in relapsing-remitting multiple sclerosis. Ann Neurol 15:250–256
Kurtzke JF (1983) Rating neurologic impairment in MS: An expanded disability status scale (EDSS). Neurology 33:1444–1452
Mertens HG, Hertel G, Reuther P, Ricker K (1981) Effects of immunosuppressive drugs (Azathioprine). Ann NY Acad Sci 377:691–699
Patzold U, Hecker H, Pocklington P (1982) Azathioprine in treatment of multiple sclerosis. Final results of a 4 1/2 year controlled study of its effectiveness covering 115 patients. J Neurol Sci 54: 377–394
Reinherz EL, Weiner HL, Hauser SL, Cohen JA, Distaso JA, Schlossman SF (1980) Loss of suppressor T cells in multiple sclerosis. Analysis with monoclonal antibodies. N Engl J Med 303:125–129
Rogers AJ, Kahan BD (1984) Mechanisms of action and clinical application of cyclosporin in organ transplantation. Clinics Imm All 4:217–258
Rudge P (1985) The use of cyclosporin in multiple sclerosis -trial design and tolerance. In: Schindler R (ed) Cyclosporin in autoimmune diseases. Springer, Berlin Heidelberg New York Tokyo, pp 83–87
Russell DH, Matrisian L, Kibler R, Larson DF, Poulos B, Magun BE (1984) Prolactin receptors on human lymphocytes and their modulation by cyclosporin. Biochem Biophys Res Commun 121:899–906
Schumacher GA, Beebe G, Kibler RF et al. (1965) Problems of experimental trials of therapy in multiple sclerosis: Report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis. An NY Acad Sci 122:552–568
Tindall RSA, Rollins JR, Phillips JT, Grennlee RG, Belendiuk G (1986) Double blind, placebo-controlled trial to determine the efficacy of cyclosporin A in the treatment of myasthenia gravis. Neurology 36(Suppl 1)
Valderrama R, Eggers A, Stracher A, Kaldany RRJ, Kao PN (1986) Therapie in experimental myasthenia gravis. Muscle Nerve (Suppl) 86:157
Wekerle H (1985) Mysthenia gravis -Zelluläre Grundlagen von immunologischer Selbsttoleranz und Autoimmunität. Fortschr Myol 4/2:33–37
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Kappos, L. (1987). Cyclosporin A in der Behandlung von multipler Sklerose und Myasthenie. In: Poeck, K., Hacke, W., Schneider, R. (eds) Neuroimmunologie Spinale Krankheiten Neuropsychologie Metabolische Enzephalopathien Neurologische Notfälle Interventionelle Neuroradiologie. Verhandlungen der Deutschen Gesellschaft für Neurologie, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83201-7_5
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DOI: https://doi.org/10.1007/978-3-642-83201-7_5
Publisher Name: Springer, Berlin, Heidelberg
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