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Neuroleptika Rückschau 1952–1986, Künftige Entwicklungen pp 9–26Cite as

Neurobiochemie der Neuroleptika

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Part of the book series: Tropon-Symposium ((BAYERZNS,volume 2))

Zusammenfassung

Seit den ersten Berichten über die relativ spezifische antipsychotische Wirksamkeit des Chlorpromazins (Delay u. Deniker 1952) und des Reserpins (Kline 1954), hat sich die experimentelle Pharmakologie sehr intensiv bemüht, den Mechanismus der antipsychotischen Wirkung beider Substanzen und der vielen von ihnen abgeleiteten Verbindungen aufzuklären. Dies hat im wesentlichen zwei Gründe: Zum einen ist eine genaue Kenntnis des Wirkungsmechanismus eines Pharmakons immer noch eine der wesentlichen Grundlagen einer rationalen Pharmakotherapie. Zum anderen war die Suche nach dem Wirkungsmechanismus der Antipsychotika immer von der Hoffnung getragen, über den Wirkungsmechanismus einen Schlüssel zum Verständnis der biologischen Ursachen der Schizophrenie in die Hand zu bekommen (Carlsson 1978).

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Authors
  1. W. E. Müller
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Editors and Affiliations

  1. 24, rue des Fossés Saint Jacques, F-75005, Paris, France

    Pierre Pichot

  2. Psychiatrische Klinik der Technischen Universität, Ismaninger Str. 22, D-8000, München 80, Deutschland

    Hans-Jürgen Möller

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© 1987 Springer-Verlag Berlin Heidelberg

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Müller, W.E. (1987). Neurobiochemie der Neuroleptika. In: Pichot, P., Möller, HJ. (eds) Neuroleptika Rückschau 1952–1986, Künftige Entwicklungen. Tropon-Symposium, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83188-1_3

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  • DOI: https://doi.org/10.1007/978-3-642-83188-1_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-18197-2

  • Online ISBN: 978-3-642-83188-1

  • eBook Packages: Springer Book Archive

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