Cell Metabolic Failure in Septic Shock

  • G. Crimi
  • M. Antonelli
  • R. A. De Blasi
Conference paper
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 4)


The precise pathophysiology of septic shock is yet unknown, as is the number and the relative importance of the various mediators that are believed to initiate and maintain the syndrome. This is mainly due to the lack of adequate animal shock models [1] and the unavoidable inhomogeneity of the groups of patients studied [2]. Nonetheless, the enormous volume of research that has been performed in this field, particularly in the last decades, makes it possible today to trace more reliable hypotheses on the pathogenesis of septic shock, with particular emphasis on cellular and subcellular structures and functions.


Septic Shock Oxygen Free Radical Lysosomal Enzyme Intermembrane Space Humoral Mediator 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • G. Crimi
  • M. Antonelli
  • R. A. De Blasi

There are no affiliations available

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