Abstract
A hundred patients who were to undergo cerclage or conization were entered into the study, being assigned to either group A or B on a random basis, irrespective of the type of surgery planned. Group A received conventional surgery plus two-component fibrin sealant, group B received conventional surgery alone.
The objectives of the study were to demonstrate the efficacy of fibrin sealant as a sealing adjunct in cerclage and as an aid to wound healing in conization. A further objective was to evaluate the risk of hepatitis B and hepatitis non-A/non-B transmission through fibrin sealant. Efficacy results are published elsewhere; here data are presented only on the risk of viral hepatitis transmission.
Of the 100 patients who had entered the study, 69 had a sufficient number of blood samples taken to qualify for evaluation of the hepatitis risk (group A: n = 31; group B: n = 38). None of the patients in either group contracted hepatitis B or non-A/non-B.
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© 1986 Springer-Verlag Berlin Heidelberg
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Eder, G., Neumann, M., Cerwenka, R., Baumgarten, K. (1986). Preliminary Results of a Randomized Controlled Study on the Risk of Hepatitis Transmission of a Two-Component Fibrin Sealant (Tissucol/Tisseel). In: Schlag, G., Redl, H. (eds) Fibrin Sealant in Operative Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82880-5_5
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DOI: https://doi.org/10.1007/978-3-642-82880-5_5
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