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Part of the book series: Der Hautarzt ((VDGDERMATOLOGIE,volume 34))

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Zusammenfassung

Die Entdeckung des immunsuppressiven Wirkstoffs 6-Mercaptopurin, einem Antagonisten der Purinbiosynthese, fand vor jetzt mehr als 25 Jahren statt [3]. Andere Substanzen mit ähnlichen immunsuppressiven Eigenschaften sind hinzugekommen und bilden neben dem Kortison ein wichtiges Standbein der Therapie von Autoimmunkrankheiten.

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Literatur

  1. Borel JF, KJ Lafferty (1983) Cyclosporin A speculation about its mechanism of action. Transplant Proceed XV: 1881

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  2. Miescher PA, PH Beris (1984) Immunosuppressive therapy in the treatment of autoimmun diseases. Springer Semin Immunopathol 7:69

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  3. Schwartz RS, J Stack, W Dameshek (1958) The effect of 6-mercaptopurine on antibody production. Proc Soc Exp Biol Med 99:164

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  4. Schwartz RS (1984) Twenty-five years of immunosuppression. Springer Semin Immunopathol 7:3

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  5. Steinberg AD (1981) Immunoregulatory agents. In: Textbook of Rheumatology, Eds WN Kelly, ED Harris, S Ruddy, CB Sledge. WB Saunders Company, Philadelphia, London, Toronto p 841

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© 1986 Springer-Verlag Berlin Heidelberg

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Knop, J. (1986). Immunsuppressive Therapie. In: Schnyder, U.W., Wüthrich, B., Eichmann, A. (eds) Verhandlungen der Deutschen Dermatologischen Gesellschaft. Der Hautarzt, vol 34. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82597-2_35

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  • DOI: https://doi.org/10.1007/978-3-642-82597-2_35

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15844-8

  • Online ISBN: 978-3-642-82597-2

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