Skip to main content
SpringerLink
Log in

Human Tumour Immunobiology

  • Chapter
Manual of Adult and Paediatric Medical Oncology

Part of the book series: UICC International Union Against Cancer ((UICCI))

  • 51 Accesses

Abstract

Tumour cells in man must be immunologically “different” from normal cells and the human immune system must be able to “recognize” this difference. It has been demonstrated that:

  1. 1.

    Human tumour cells possess tumour-associated antigens (TAA) not present in normal tissues.

  2. 2.

    Mononuclear cells from patients bearing tumours are capable of destroying autologous tumour cells in in vitro experiments.

  3. 3.

    Plasma or serum from the tumour-bearing patient blocks the ability of that patient’s mononuclear cells to destroy autologous tumour cells.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Further Reading

  • Gale RP (1980) Autologous bonemarrow transplantations in patients with cancer. J Am Med Assoc 236:540–542

    Article  Google Scholar 

  • Hersch EM, Mavligit GM, Gutterman JU (1976) J Am Med Assoc 236:1739–1742

    Article  Google Scholar 

  • Lobuglio AF (1980) Clinical Immunotherapy. Marcel Dekker, New York

    Google Scholar 

  • MacDonald JS (1976) The immunobiology of colorectal cancer. Semin Oncol 3:421–432

    Google Scholar 

  • Oettgen HF (1977) Immunotherapy of cancer. N Engl J Med 297:484–491

    Article  PubMed  CAS  Google Scholar 

  • Sikora K (1980) Does interferon cure cancer? Brit Med J 281:855–858

    Article  PubMed  CAS  Google Scholar 

  • Stevenson GT, Laurence DJR (1975) The Immune Response to Human Tumours in Man. UICC Technical Report Series, Vol 22. UICC, Geneva

    Google Scholar 

  • Terry WD, Windhorst D (Eds). (1978) Immunotherapy of Cancer: Present Status of Trials in Man. Raven Press, New York

    Google Scholar 

  • Waldmann TA, et al. (1978) Disorders of suppressor immunoregulatory cells in the pathogenesis of immunodeficiency and autoimmunity. Ann Intern Med 88:226–235

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centro Riferimento Oncologico, Via Pedemontana, 33081, Aviano (Pordenone), Italy

    Dr. S. Monfardini (Chairman) & Dr. A. Veronesi

  2. Onkologie-Abteilung, Inselspital, Freiburgstraße, 3010, Bern, Switzerland

    Prof. K. Brunner

  3. Manchester University and Christie Hospital and Holt Radium Institute, Winslow Road, Manchester, M20 9BX, UK

    Prof. D. Crowther

  4. National Institute of Oncology, XII. Rath Gyorgy-u 7-9, Budapest, 1525, Hungary

    Prof. S. Eckhardt

  5. Service de Médécine Infantille II, Hopital d’Enfants Allée du Morovan, 54120, Vandoeuvre-Les-Nancy, France

    Prof. D. Olive

  6. Akademie der Wissenschaften der DDR, Robert-Roessle-Institut, Lindenberger Weg 80, 1115, Berlin-Buch, G.D.R.

    Prof. S. Tanneberger

  7. CRC Medical Oncology Unit, Centre Block CF99, Southampton General Hospital, Southampton, S09 4XY, UK

    Prof. J. M. A. Whitehouse

  8. Division of Cancer Treatment, Dept. of Health, Education and Welfare, National Institute of Health, Bethesda, MD, 20205, USA

    Dr. R. Wittes

Authors
  1. Dr. S. Monfardini
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Prof. K. Brunner
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Prof. D. Crowther
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Prof. S. Eckhardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Prof. D. Olive
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Prof. S. Tanneberger
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Dr. A. Veronesi
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Prof. J. M. A. Whitehouse
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Dr. R. Wittes
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Centro Riferimento Oncologico, Via Pedemontana, 33081, Aviano (Pordenone), Italy

    S. Monfardini (Chairman) & A. Veronesi (Chairman) & 

  2. Onkologie-Abteilung, Inselspital, Freiburgstraße, 3010, Bern, Switzerland

    K. Brunner

  3. Manchester University and Christie Hospital and Holt Radium Institute, Winslow Road, Manchester, M20 9BX, UK

    D. Crowther

  4. National Institute of Oncology, XII. Ráth Gyorgy-u 7-9, Budapest, 1525, Hungary

    S. Eckhardt

  5. Service de Médécine Infantille II, Hopital d’Enfants Allée du Morovan, 54120, Vandoeuvre-Les-Nancy, France

    D. Olive

  6. Robert-Roessle-Institut, Akademie der Wissenschaften der DDR, Lindenberger Weg 80, 1115, Berlin-Buch, G.D.R.

    S. Tanneberger

  7. CRC Medical Oncology Unit, Centre Block CF 99, Southampton General Hospital, Southampton, S09 4XY, UK

    J. M. A. Whitehouse

  8. Division of Cancer Treatment, Dept. of Health, Education and Welfare, National Institute of Health, Bethesda, MD, 20205, USA

    R. Wittes

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Monfardini, S. et al. (1987). Human Tumour Immunobiology. In: Monfardini, S., et al. Manual of Adult and Paediatric Medical Oncology. UICC International Union Against Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82489-0_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-82489-0_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15347-4

  • Online ISBN: 978-3-642-82489-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation