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Soft-Tissue Sarcoma

  • S. Monfardini
  • K. Brunner
  • D. Crowther
  • S. Eckhardt
  • D. Olive
  • S. Tanneberger
  • A. Veronesi
  • J. M. A. Whitehouse
  • R. Wittes
Part of the UICC International Union Against Cancer book series (UICCI)

Abstract

Soft-tissue sarcomas are a rare group of tumours comprising approximately 1% of all malignant tumours. The annual age-adjusted incidence is 2 per 100000. Conventional management has relied heavily on surgery, but the inadequacy of this approach is reflected by local recurrence rates of 40%–80% in adult sarcomas and of as high as 90% in childhood sarcomas. Suit et al., treating 100 patients with localized soft-tissue sarcoma using limited surgery and high-dose radiation therapy, made the following observations:
  1. 1.

    Histological grade affected prognosis (disease-free survivals of 86% for grade I tumours compared with 17% for grade III).

     
  2. 2.

    Size of the primary tumour determined the subsequent local recurrence rate (18% for tumours < 5 cm compared with 8% for those 5 cm).

     
  3. 3.

    Site of the primary tumour was important (local recurrence rate 33% for proximal site compared with 5% for a distal site).

     

Keywords

Local Recurrence Local Recurrence Rate Testicular Cancer Synovial Sarcoma Fibrous Histiocytomas 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Further Reading

  1. Bramwell VHC, Pinedo HM (1980) Bone and soft tissue sarcomas. In: Cancer Chemotherapy 1980. Pinedo HM (Ed). Excerpta Medica, AmsterdamGoogle Scholar
  2. Van Oosterom AT, Muggia FM, Cleton FJ (1980) Therapeutic Progress in Ovarian Cancer, Testicular Cancer and the Sarcomas. Leiden University Press, LeidenCrossRefGoogle Scholar
  3. Monfardini S, Gianni C, Lombardi F, Fossati-Bellani F (1979) Chemotherapy and controlled studies in soft-tissue sarcomas. In: Advances in Medical Oncology, Research and Education. Vol 10. Kumar S (Ed). Pergamon Press, OxfordGoogle Scholar
  4. Sears HF, Hopson R, Inouye W et al. (1980) Analysis of staging and management of patients with sarcoma: a ten year experience. Ann Surg 91:488CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • S. Monfardini
    • 1
  • K. Brunner
    • 2
  • D. Crowther
    • 3
  • S. Eckhardt
    • 4
  • D. Olive
    • 5
  • S. Tanneberger
    • 6
  • A. Veronesi
    • 1
  • J. M. A. Whitehouse
    • 7
  • R. Wittes
    • 8
  1. 1.Centro Riferimento OncologicoAviano (Pordenone)Italy
  2. 2.Onkologie-AbteilungInselspitalBernSwitzerland
  3. 3.Manchester University and Christie Hospital and Holt Radium InstituteManchesterUK
  4. 4.National Institute of OncologyBudapestHungary
  5. 5.Service de Médécine Infantille IIHopital d’Enfants Allée du MorovanVandoeuvre-Les-NancyFrance
  6. 6.Akademie der Wissenschaften der DDRRobert-Roessle-InstitutBerlin-BuchG.D.R.
  7. 7.CRC Medical Oncology Unit, Centre Block CF99Southampton General HospitalSouthamptonUK
  8. 8.Division of Cancer Treatment, Dept. of Health, Education and WelfareNational Institute of HealthBethesdaUSA

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