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Basic Concepts in Cancer Chemotherapy

  • S. Monfardini
  • K. Brunner
  • D. Crowther
  • S. Eckhardt
  • D. Olive
  • S. Tanneberger
  • A. Veronesi
  • J. M. A. Whitehouse
  • R. Wittes
Chapter
Part of the UICC International Union Against Cancer book series (UICCI)

Abstract

Chemotherapy is planned on the basis of observed differences between normal and tumour cells in response to antitumour agents used both singly and in combination. Part of the difference between normal and neoplastic cells can be explained by consideration of proliferative characteristics; however, it must be emphasized that cell kinetics cannot explain all the consequences of tumour cell exposure to a drug, since these are also dependent upon pharmacokinetics, biochemistry and tumour biology.

Keywords

Cancer Chemotherapy Cytosine Arabinoside Growth Fraction Anthracycline Antibiotic Antitumour Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Further Reading

  1. 1.
    Kuemmerle HP, Berkarda B, KarrerK, Mathe G (eds) (1984) Antineoplastic chemotherapy. (Clinical Chemotherapy; Vol III) Thieme-Stratton Inc, New York, 587 SGoogle Scholar
  2. 2.
    Knobf MKT, Fischer DS, Welch-McCaffrey D (1984) Cancer Chemotherapy-Treatment and care. 2nd ed. GK Hall Med Publ, Boston, 343 SGoogle Scholar
  3. 3.
    Greenspan EM (1982) Clinical interpretation and practice of cancer chemotherapy. Raven Press, New York, 666 SGoogle Scholar
  4. 4.
    Brunner KW, Nagel GA (Hrsg) (1985) Internistische Krebstherapie. 3. völlig überarb Aufl. Springer, Berlin Heidelberg New York, 576 SGoogle Scholar
  5. 5.
    Tanneberger St (ed) (1986) Experimentelle und klinische Chemotherapie. Akademie-Verlag, Berlin, Gustav Fischer Verlag, Stuttgart New York 1980Google Scholar
  6. 6.
    Caiman KC, Smyth JF, Tattersall M (1980) Basic Principles of Cancer Chemotherapy. Macmillan Press, London BasinstokeGoogle Scholar
  7. 7.
    Carter StK, Bakowski MT, Hellmann K (1981) Chemotherapy of Cancer. J Wiley & Sons, New York London Sydney TorontoGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • S. Monfardini
    • 1
  • K. Brunner
    • 2
  • D. Crowther
    • 3
  • S. Eckhardt
    • 4
  • D. Olive
    • 5
  • S. Tanneberger
    • 6
  • A. Veronesi
    • 1
  • J. M. A. Whitehouse
    • 7
  • R. Wittes
    • 8
  1. 1.Centro Riferimento OncologicoAviano (Pordenone)Italy
  2. 2.Onkologie-AbteilungInselspitalBernSwitzerland
  3. 3.Manchester University and Christie Hospital and Holt Radium InstituteManchesterUK
  4. 4.National Institute of OncologyBudapestHungary
  5. 5.Service de Médécine Infantille IIHopital d’Enfants Allée du MorovanVandoeuvre-Les-NancyFrance
  6. 6.Akademie der Wissenschaften der DDRRobert-Roessle-InstitutBerlin-BuchG.D.R.
  7. 7.CRC Medical Oncology Unit, Centre Block CF99Southampton General HospitalSouthamptonUK
  8. 8.Division of Cancer Treatment, Dept. of Health, Education and WelfareNational Institute of HealthBethesdaUSA

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