Rationale for Perioperative Anticancer Treatment
I will limit my discussion essentially to chemotherapy as an adjuvant to surgery, since my experience is in this field, but I recognize that radiation therapy could be substituted for surgery in many cases and also that there are clinical examples of all three modalities being used in proper sequences with improved results over any two-modality treatment. I would like to begin with a brief discussion of the need for perioperative chemotherapy.
KeywordsAdjuvant Chemotherapy Body Burden Lewis Lung Carcinoma Tumor Stem Cell Systemic Cancer
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- DeVita VT Jr, Henney JE, Stonehill E (1979) Cancer mortality: the good news. In: Jones SE, Salmon SE (eds) Adjuvant therapy of cancer II. Grune and Stratton, New York, pp XV-XXGoogle Scholar
- Schabel FM Jr (1976) Concepts for treatment of micrometastases developed in murine systems. AJ1 126:500–511Google Scholar
- Schabel FM Jr, Simpson-Herren L (to be published) Tumor growth kinetics and drug treatment of cancer. In: Kuemmerle HP, Karrer K, Mathé G, Periti P (eds) Clinical chemotherapy, vol 3. Anticancer chemotherapy. Thieme, StuttgartGoogle Scholar