Measurement of Pulmonary Capillary Perfusion in Intubated Patients with a Non-invasive N2O-Rebreathing Method
The study describes a method for the measurement of pulmonary capillary perfusion in intubated animals.
The results were compared with measurements taken with a Swan-Ganz catheter using Fick’s formula. The statistical analyses show a difference of ± 10% between the two methods.
First clinical trials in intensive care patients show the reproducibility and accuracy of this method to be satisfactory. It must be remembered that this method measures only the perfusion of those parts of the lung which take part in the gas exchange. The perfusion measured by the N2O-rebreathing method can only be taken as cardiac tidal volume if the gas exchange is normal. This makes it possible to recognize intrapulmonary changes in microcirculation.