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Management of Chronic Myelogenous Leukemia and Blastic Crisis

  • Chapter
Leukemia

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 93))

Abstract

Chronic myelogenous leukemia (CML) is a neoplastic disease of the hematopoietic system that results from a mutation in a single pluripotential stem cell. The abnormal stem cell receives a growth advantage, while for unknown reasons the proliferation of regular hematopoiesis is inhibited. Excessive and unrestrained growth of blood progenitor cells leads to an accumulation of mature and immature cells in the peripheral blood and to clinical manifestations due to organ infiltrations by extramedullar hematopoiesis.

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Authors and Affiliations

  1. II. Innere Klinik, Krankenhaus Moabit, Turmstrasse 21, 1000, Berlin 21, Germany

    K. P. Hellriegel

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  1. K. P. Hellriegel
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  1. Institut für Hämatologie, Abteilung für Immunologie, Gesellschaft für Strahlen- und Umweltforschung mbH, Landwehrstrasse 61, 8000, München 2, Germany

    Eckhard Thiel  & Stephan Thierfelder  & 

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© 1984 Springer-Verlag Berlin · Heidelberg

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Hellriegel, K.P. (1984). Management of Chronic Myelogenous Leukemia and Blastic Crisis. In: Thiel, E., Thierfelder, S. (eds) Leukemia. Recent Results in Cancer Research, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82249-0_11

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  • DOI: https://doi.org/10.1007/978-3-642-82249-0_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82251-3

  • Online ISBN: 978-3-642-82249-0

  • eBook Packages: Springer Book Archive

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