Skip to main content

Part of the book series: Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology ((HDBRADIOL,volume 20))

  • 60 Accesses

Zusammenfassung

Die Abdominalorgane sind relativ strahlenempfindlich und haben deshalb seit jeher der Strahlentherapie der Tumoren des Abdominalraums (mit Ausnahme der Tumoren des kleinen Beckens) enge Grenzen gesetzt. Wenn auch die pathogenetischen Mechanismen aller akuten Strahlenfolgen der verschiedenen Organe wie auch aller chronischen Strahlenfolgen jeweils gleich sind [im übrigen ja die gleichen wie an der Haut, wo sie im Detail beschrieben werden (s.S. 176ff.)], sind die klinischen und pathomorphologischen Folgezustände entsprechend der unterschiedlichen Struktur und Funktion der verschiedenen Organe doch so unterschiedlich, daß eine separate Darstellung der Strahlenfolgen von Magen, Darm und Leber angezeigt ist. Angesichts der zum Teil kaum mehr zu übersehenden Fülle von klinischen und experimentellen Arbeiten (insbesondere über die Strahlenreaktion des Darms) kann nur eine thematisch eng begrenzte Auswahl zur Darstellung der heute für klinisch relevant erachteten Probleme herangezogen werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Abe M, Takahashi M (1981) Intraoperative radiotherapy: The Japanese experience. Int J Radiat Oncol Biol Phys 7: 863–868

    Article  PubMed  CAS  Google Scholar 

  • Archambeau J, Griem M, Harper P (1966) The effects of 250 kV X-rays on the dog’s pancreas: morphological and functional changes. Radiat Res 28: 243–256

    Article  PubMed  CAS  Google Scholar 

  • Battermann JJ, Hart GAM, Breur K (1981) Dose-effect relations for tumour control and complication rate after fast neutron therapy for pelvic tumours. Br J Radiol 54: 899–904

    Article  PubMed  CAS  Google Scholar 

  • Berthrong M, Fajardo LF (1981) Radiation injury in surgical pathology, II, Alimentary tract. Am J Surg Pathol 5: 153–178

    Article  PubMed  CAS  Google Scholar 

  • Bicher HI, Ashbrook DW, Harris DR, Dalrymple GV (1976) Changes in platelet and microcirculation function induced by ionizing radiation to the liver. Int J Radiat Oncol Biol Phys 1: 679–685

    Article  PubMed  CAS  Google Scholar 

  • Birzle H, Franzius E (1965) Über die funktionelle Strahlenempfindlichkeit der Leber. Strahlentherapie 126: 119–131

    PubMed  CAS  Google Scholar 

  • Birzle H, Beck K, Nusselt L (1970) Die Wirkung gezielter Röntgentiefenbestrahlung der Leber auf deren Entgiftungsleistung durch Paarung mit Glucuronsäure beim Kaninchen. Strahlentherapie 139: 347–353

    PubMed  CAS  Google Scholar 

  • Black WC, Ackermann LV (1965) Carcinoma of the large intestine as a late complication of pelvic radiotherapy. Clin Radiol 16: 278–281

    Article  PubMed  Google Scholar 

  • Black WC, Gomez LS, Yuhas JM, Kligermann MM (1980) Quantitation of the late effects of X-radiation on the large intestine. Cancer 45: 444–451

    Article  PubMed  CAS  Google Scholar 

  • Bowers RF, Brick JB (1947) Surgery in radiation in injury of the stomach. Surgery 22: 20–40

    PubMed  CAS  Google Scholar 

  • Brase A, Bockslaff H, Kaufmann M (1972) Szintigra-phische Befunde der Leber nach Teilbestrahlung mit Kobalt 60. Strahlentherapie 143: 41–47

    PubMed  CAS  Google Scholar 

  • Brase A, Bockslaff H, Heindl H, Järivinen S (1973) Tierexperimentelle Funktionsuntersuchungen mit Radionukliden an der Leber nach gezielter Co-60 Bestrahlung. Strahlentherapie 146: 198–207

    PubMed  CAS  Google Scholar 

  • Brase A, Bockslaff H, Emminger E (1974) Angiographische Untersuchungen der portalen LebergefäBe bei Kaninchen nach Strahleninsult. Strahlentherapie 147: 278–289

    PubMed  CAS  Google Scholar 

  • Braun H (1963) Leber. In: Scherer E, Stender HS (Hrsg) Strahlenpathologie der Zelle. Thieme, Stuttgart

    Google Scholar 

  • Brick IB (1947) The effect of large dosages of irradia- tion gastric acidity. N Engl J Med 237: 48–51

    Article  PubMed  CAS  Google Scholar 

  • Browde S, Mohr N de (1982) Non-standard fractionation schemes in the treatment of advanced carcinoma of the uterine cervix and advanced head and neck cancer. In: Nervi C, Fletcher GH (eds) The biological and clinical basis of radioresistance. Thomas, Springfield

    Google Scholar 

  • Bruegel C (1917) Die Beeinflussung des Magenchemismus durch Röntgenstrahlen. Muench Med Wochenschr 64: 379–382

    Google Scholar 

  • Carpender JWJ, Levin E, Clapman LB, Miller RE (1956) Radiation in the therapy of peptic ulcer. Am J Roentgenol 75: 374–379

    CAS  Google Scholar 

  • Chen KY, Withers HR (1972) Survival characteristics of stem cells of gastric mucosa subjected to localized gamma irradiation. Int J Radiat Biol 21: 521–534

    Article  CAS  Google Scholar 

  • Coggle JE (1968) Effect of cell cycle on recovery from radiation damage in the mouse liver. Nature 217: 180–182

    Article  PubMed  CAS  Google Scholar 

  • Concannon JP, Edelmann A, Rich JC, Kunkel G (1967) Localized “radiation hepatitis” as demonstrated by scintillation scanning. Radiology 89: 136–139

    PubMed  CAS  Google Scholar 

  • Cottier H (1961) Strahlenbedingte Lebensverkür- zung. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Craig MS, Buie LA (1949) Factitial (irradiation) proctitis. A clinicopathological study of 200 cases. Surgery 25: 472–487

    PubMed  Google Scholar 

  • Cronkite EP, Fliedner TM (1972) The radiation syndromes. In: Hug O, Zuppinger A (Hrsg) Strahlenbiologie 3. Springer, Berlin Heidelberg New York, S (Handbuch der Medizinischen Radiologie, Bd II/3

    Google Scholar 

  • Delclos L, Braun EJ, Herrera JR, Sanpiere VC, Rosenbeek E van (1963) Whole abdominal irradiation with Co-60 moving strip technic. Radiology 81: 632–641

    PubMed  CAS  Google Scholar 

  • Dethlefsen LA, Riley RM (1979) The effects of adriamycin and X-irradiation on the murine duodenum. Int J Radiat Oncol 5: 507–513

    Article  CAS  Google Scholar 

  • Dettmer CA, Kramer S, Driscoll DH, Aponte GE (1968) A comparison of the chronic effects of irradiation upon the normal, damaged, and regenerating rat liver. Radiology 91: 993–997

    Google Scholar 

  • Doig RK, Funder JF, Weiden S (1951) Serial gastric biopsy studies in a case of duodenal ulcer treated by deep X-ray therapy. Med J Aust 38: 828–830

    Google Scholar 

  • Duncan W, Leonard JC (1965) The malabsorption syndrome following radiotherapy. QJ Med 34: 319–329

    CAS  Google Scholar 

  • Edwards DN (1968) Complications following mega-voltage radiation for carcinoma of the bladder. Clin Radiol 19: 27–33

    Google Scholar 

  • Ellinger F (1957) Medical radiation biology, Thomas, Springfield

    Google Scholar 

  • Engelstad RB (1938) The effect of roentgen on the stomach in rabbits. Am J Roentgenol 40: 243–263

    Google Scholar 

  • Fabrikant JI (1967) Cell proliferation in the regenerating liver of continuously irradiated mice. Br J Radiol 40: 487–495

    Article  PubMed  CAS  Google Scholar 

  • Fajardo LF, Berthrong M (1981) Radiation injury in surgical pathology, III, Am J Surg Pathol 5: 279–296

    Article  PubMed  CAS  Google Scholar 

  • Findley JM, Newaisky GA, Sircus W, McManus JPA (1974) Role of gastric irradiation in management of peptic ulceration and esophagitis. Br Med J 3: 769–771

    Article  Google Scholar 

  • Gauwerky F (1949) Die Komplikationen bei der Radiumbehandlung der Kollumkarzinome and ihre Bedeutung für den Behandlungserfolg. Strahlentherapie 80: 51–70

    Google Scholar 

  • Gelfand MD, Tepper M, Katz LA, Binder HJ, Yesner R, Floch MH (1968) Acute irradiation proctitis in man. Development of eosinophilic crypt abcesses. Gastroenterology 54: 401–411

    PubMed  CAS  Google Scholar 

  • Geraci JP, Jackson KL, Christensen GM, Parker RG, Fox MS, Thrower PD (1974) The relative biological effectiveness of cyclotron fast neutrons for early and late damage to the small intestine of the mouse. Eur J Cancer 10: 99–102

    Article  PubMed  CAS  Google Scholar 

  • Geraci JP, Jackson KL, Christensen GM, Thrower PD, Weyer BJ (1977) Acute and late damage in the mouse small intestine following multiple fractionations of neutrons or X-rays. Int J Radiat Oncol Biol Phys 2: 693–696

    Article  PubMed  CAS  Google Scholar 

  • Geraci JP, Jackson KL, Thrower PD, Mariano MS (1980) Relative biological effectiveness of cyclotron fast neutrons for late hepatic injury in rats. Radiat Res 82: 570–578

    Article  PubMed  CAS  Google Scholar 

  • Goldgraber MB, Rubin CE, Palmer WL, Dobson RL, Massey BW (1954) The early gastric response to irradiation. A serial biopsy study. Gastroenterology 27: 1–20

    PubMed  CAS  Google Scholar 

  • Goodrich JK, Hickmann BT (1962) Oleic acid I131 intestinal absorption in pelvic CO“ irradiation. Am J Roentgenol 87: 69–75

    CAS  Google Scholar 

  • Graudinns J (1969) Über Strahlenspätschäden am Dünndarm. Langenbecks Arch Chir 324: 120–130

    Article  Google Scholar 

  • Gray MJ, Kottmeier HL (1957) Rectal and bladder injuries following radium therapy for carcinoma of the cervix at the radiumhemmet. Am J Obstet Gynecol 74: 1294–1303

    PubMed  CAS  Google Scholar 

  • Hamilton E (1978) Cell proliferation and ageing in mouse colon. Repopulation after repeated X-ray injury in young and old mice. Cell Tiss Kinet 11: 423–431

    CAS  Google Scholar 

  • Hamilton FE (1947) Gastric ulcer following radiation. Arch Surg 55: 394–399

    Article  PubMed  CAS  Google Scholar 

  • Haot J (1965) Contribution à l’étude de l’ulcere radiologique de l’estomac. Rev Belg Pathol Med Exp 31: 203–225

    PubMed  CAS  Google Scholar 

  • Hebard DW, Jackson KL, Christensen GM (1980) The chronological development of late radiation injury in the liver of the rat. Radiat Res 81: 441–454

    Article  PubMed  CAS  Google Scholar 

  • Heyde W, Schmermund HJ (1953) Zur Vermeidung von Darmschäden bei der intravaginalen Bestrahlung des Kollumkarzinoms. Geburtshilfe Frauenhkd 13: 392–401

    CAS  Google Scholar 

  • Hornsey S, Alper T (1966) Unexpected dose-rate effect in the killing of mice by radiation. Nature 210: 212–213

    Article  PubMed  CAS  Google Scholar 

  • Hubmann FH (1981) Effect of X-irradiation on the rectum of the rat. Br J Radiol 54: 250–254

    Article  PubMed  CAS  Google Scholar 

  • Hueper WC, Carvajal-Forero J de (1944) The effect of repeated irradiation of the gastric region with small doses of Roentgen rays upon the stomach and blood of dogs. Am J Roentgenol 52: 529–534

    Google Scholar 

  • Hug O, Kellerer AM, Zuppinger A (1966) Der Zeitfaktor. In: Handbuch der medizinischen Radiologie, Bd II/1. In: Zuppinger A (Hrsg) Strahlenbiologie 1. Springer, Berlin Heidelberg New York, S 271–354

    Google Scholar 

  • Ingold JA, Reed GB, Kaplan HS, Bagshaw MA (1965) Radiation Hepatitis. Am J Roentgenol 93: 200–208

    CAS  Google Scholar 

  • Johnson PM, Grossman FM, Atkins HL (1967) Radiation induced hepatic injury, its detection by scintillation scanning. Am Roentgenol 99: 453–462

    CAS  Google Scholar 

  • Kelly LS, Hirsch JD, Beach G, Palmer W (1956) The time function of P32 incorporation into DNA of regenerating liver; the effect of irradiation. Cancer Res 16: 117–121

    Google Scholar 

  • Kinzie J, Studer RK, Perez B, Potchen EJ (1972) Noncytokinetic radiation injury: anticoagulants as radioprotective agents in experimental radiation hepatitis. Science 175: 1481–1483

    Article  PubMed  CAS  Google Scholar 

  • Kiszel Z (1983) Untersuchungen über die chronischen Strahlenfolgen am Enddarm der Ratte nach lokaler Bestrahlung. Dissertation medizinische Fakultät, Universität München

    Google Scholar 

  • Kolb JJ (1982) Knochenmarkstransplantation: Theoretische Grundlagen, vorklinische Studien und klinische Anwendung. Habilitationsarbeit, Medizinische Fakultät der Universität München

    Google Scholar 

  • Kolb JJ, Rieder I, Bodenberger B, Netzel B, Schaffer E, Kolb H, Thierfelder S (1979) Dose rate and dose fractionation studies in total body irradiation of dogs. Pathol Biol (Paris) 27: 370–372

    CAS  Google Scholar 

  • Kottmeier HL, Gray MJ (1961) Rectal and bladder injuries in relation to radiation dosage in carcinoma of the cervix. A 5 year follow-up. Am J Obstet Gynecol 82: 74–82

    PubMed  CAS  Google Scholar 

  • Kovacs L (1976) Histologische Untersuchungen von Pankreasveränderungen verursacht durch experimentelle, fraktionierte, lokale Bestrahlung. Strahlentherapie 152: 455–468

    PubMed  CAS  Google Scholar 

  • Kurohara SS, Swensson NL, Usselmann JA, George FW (1967) Response and recovery of liver to radiation as demonstrated by photoscan. Radiology 89: 129–135

    PubMed  CAS  Google Scholar 

  • Lenk R (1926) Die Röntgentherapie der Erkrankungen des Verdauungstraktes. In: Meyer H (Hrsg) Lehrbuch der Strahlentherapie, Bd III. Urban Schwarzenberg, Berlin Wien, S 451–486

    Google Scholar 

  • Lewin K, Millis RR (1973) Human radiation hepatitis. A morphologic study with emphasis on the late changes. Arch Pathol 96: 21–26

    PubMed  CAS  Google Scholar 

  • Marciàl VA, Santiago EA, Lanaro EA, Castro-Vita H, Arroyo G, Moscol JA, Gomez C, Velasquez J, Prado K (1977) Radiation-induced liver damage. In: Radiobiological research and radiotherapy, vol II. International Atomic Agency, Wien

    Google Scholar 

  • Matsuzawa T, Wilson R (1965) The intestinal mucosa of germfree mice after whole body X-irradiation with 3 kiloroentgens. Radiat Res 25: 15–24

    Article  PubMed  CAS  Google Scholar 

  • Morgenstern L, Thompson R, Friedman NB (1977) The modern enigma of radiation enteropathy: sequelae and solutions. Am J Surg 134: 166–172

    Article  PubMed  CAS  Google Scholar 

  • Neumeister K (1973) Die Strahlenreaktionen des Gastrointestinaltraktes. Thieme, Leipzig

    Google Scholar 

  • Ogata K, Hizawa K, Yoshida M, Kitamuro T, Akagi G, Kagawa K, Fukuda F (1963) Hepatic injury following irradiation — a morphologic study. Tokushima Journal of experimental Medicine 9: 240–251

    Google Scholar 

  • Palmer WL, Templeton F (1939) The effect of radiation therapy on gastric secretion. JAMA 112: 1429–1434

    Article  Google Scholar 

  • Phillips TL (1980) Tissue toxicity of Radiation-Drug Interactions. In: Sokol GH, Maickel RP (eds) Radiation-Drug Interactions in the treatment of cancer. Wiley, New York Chichester Brisbane Toronto

    Google Scholar 

  • Phillips TL, Fu KK (1976) Quantification of combined radiation therapy and chemotherapy effects on critical normal tissues. Cancer 37: 1186–1200

    Article  PubMed  CAS  Google Scholar 

  • Powel-Smith C (1965) Factors influencing the incidence of radiation injury in cancer of the cervix. J Ass Canad Radiol 16: 132–137

    CAS  Google Scholar 

  • Quastler H (1956) The nature of intestinal radiation death. Radiat Res 4: 303–320

    Article  PubMed  CAS  Google Scholar 

  • Reed GB, Cox AJ (1966) The human liver after radiation injury. Am J Pathol 48: 597–611

    PubMed  Google Scholar 

  • Reeves RJ, Cavanaugh PJ, Sharpe KW, Thorne WA, Winkler C, Sanders AP (1959) Fat absorption from human gastrointestinal tract in patients undergoing radiation therapy. Radiology 73: 398–401

    PubMed  CAS  Google Scholar 

  • Reeves RJ, Sanders AP, Isley JK, Sharpe KW, Baylin GJ (1965) Fat absorption studies and small bowel X-Ray studies in patients undergoing Co“ teletherapy and or radium application. Am J Roentgenol 94: 848–851

    CAS  Google Scholar 

  • Ricketts WE, Palmer WL, Kirner JB, Hamann A (1948) Radiation therapy in peptic ulcer. An analysis of results. Gastroenterology 11: 789–806

    PubMed  CAS  Google Scholar 

  • Roswit B, Malsky SJ, Reid CB (1972) Radiation tolerance of the gastrointestinal tract. Front Radiat Ther Oncol 6: 160–181

    Google Scholar 

  • Rübe W, Seegelken K (1974) Dickdarmstenosen nach Bestrahlung von Nierentumoren. Strahlentherapie 147: 63–68

    PubMed  Google Scholar 

  • Rubin P, Casarett GW (1968) Clinical radiation pathology. Saunders, Philadelphia London Toronto

    Google Scholar 

  • Schenken LL, Burholt DR, Hagemann RF, Lesher S (1976) The modification of gastrointestinal tolerance and responses to abdominal irradiation by chemotherapeutic agents. Radiology 120: 417–420

    PubMed  CAS  Google Scholar 

  • Senn A, Lundsgard-Hansen P (1956) Diagnose und Therapie der Bestrahlungsschäden am Gastroin-testinaltrakt. Schweiz Med Wochenschr 86: 1015–1020

    PubMed  Google Scholar 

  • Singh K (1978) Two regimes with the same TDF but differing morbidity used in the treatment of stage III carcinoma of the cervix. Br J Radiol 51: 357–362

    Article  PubMed  CAS  Google Scholar 

  • Swift MN, Taketa ST, Bond VP (1955) Delayed gastric emtying in rats after whole and partial body irradiation. Am J Physiol 182:479-

    Google Scholar 

  • Takahashi T (1964) A study on preoperative and postoperative telecobalt therapy in gastric cancer. Three year results of Co“ irradiation following palliative gastric resection. Nippon Acta Radiol 24: 129–132

    PubMed  CAS  Google Scholar 

  • Tefft M, Mitus A, Das L, Vawter GF, Filler RM (1970) Irradiation of the liver in children: review of experience in the acute and chronic phases, and in the intact normal and partially resected. Am J Roentgenol 108: 365–385

    CAS  Google Scholar 

  • Thames HD, Withers HR, Peters LJ, Fletcher GH (1982) Changes in early and late radiation responses with dose fractionation. Implications for dose-survival relationships. Int J Radiat Oncol 8: 219–222

    Article  Google Scholar 

  • Usselman JA (1965) Liver scanning in the assessment of liver damage from therapeutic external irradiation. J Nucl Med 6: 353–364

    Google Scholar 

  • Warren SH, Friedman NP (1942) Pathology and pathological diagnosis of radiation lesions in the gastrointestinal tract. Am J Pathol 18: 499

    PubMed  CAS  Google Scholar 

  • Wharton JT, Delclos L, Gallager S, Smith JP (1973) Radiation hepatitis induced by abdominal irradiation with the cobalt-60 moving strip technique. Am J Roentgenol 117: 73–80

    CAS  Google Scholar 

  • Wiernik G, Plant M (1970) Radiation effects on the human intestinal mucosa. Curr Top Radiat Res 7:327–368

    Google Scholar 

  • Wiley HM, Sugarbaker ED (1950) Roentgenotherapeutic changes in the small intestine. Surgical aspects. Cancer 3: 629–640

    Article  PubMed  CAS  Google Scholar 

  • Withers HR, Elkind MM (1968) Radiosensitivity and fractionation response of crypt cells of mouse jejunum. Radiat Res 38: 598–613

    Article  Google Scholar 

  • Withers HR, Elkind MM (1970) Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation. Int J Radiat Biol 17: 261–267

    Article  CAS  Google Scholar 

  • Withers HR, Mason KA (1974) The kinetics recovery in irradiated colonic mucosa of the mouse. Cancer 34: 896–904

    Article  PubMed  Google Scholar 

  • Zollinger HU (1960) Radiohistologie und Radiohistopathologie. In: Roulet F (Hrsg) Strahlung und Wetter. Handbuch der Pathologie, Bd X/1. Springer, Berlin Heidelberg New York, S 127

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Springer-Verlag Berlin · Heidelberg

About this chapter

Cite this chapter

Trott, KR. (1985). Strahlenwirkungen auf die Abdominalorgane. In: Heuck, F., Scherer, E. (eds) Strahlengefahrdung und Strahlenschutz / Radiation Exposure and Radiation Protection. Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82229-2_3

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-82229-2_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82230-8

  • Online ISBN: 978-3-642-82229-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics