Endocrine Surgery in Breast Cancer

  • F. Badellino
  • G. Canavese
  • G. Margarino
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 91)


Endocrine cancer therapy began its development only after the availability of synthetic steroids made bilateral adrenalectomy and hypophysectomy possible.


Breast Cancer Diabetic Retinopathy Male Breast Cancer Sella Turcica Bilateral Adrenalectomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Badellino F (1976) Results of pituitary ablation by %Y and 32P interstitial implants in breast carcinoma. In: Eharyulu KKN, Sudarsanam A (eds) Hormones and cancer. Stratton Medical, New York, p 233Google Scholar
  2. 2.
    Brown PW, Terz JJ, King R, Lawrence W Jr (1975) Bilateral adrenalectomy for metastatic breast carcinoma. Arch Surg 110: 77PubMedCrossRefGoogle Scholar
  3. 3.
    Bucalossi P, Veronesi U, Cascinelli N, Buraggi G, Miserocchi E, Monfardini S (1976) Pituitary ablation with 90Y implant in advanced thyroid cancer. Cancer 20: 724CrossRefGoogle Scholar
  4. 4.
    Caldarola L, Badellino F, Molinatti GM (1971) Ovariectomie avec surrénalectomie bilatérale pour cancer du sein en stade avancé (A propos de 118 cas). Presse Med 79: 1743PubMedGoogle Scholar
  5. 5.
    Caldarola L, Badellino F, Santoro L, Lesca F, Reali F, Ferrerò B (1973) Resultati a distanza in 73 ipofisectomie radiobiologiche per cancri mammari inoperabili e/o metastatizzati. Gaz Med Ital 132: 276Google Scholar
  6. 6.
    Catania VC, Paolucci R (1977) Indicazioni, risultati e prospettive della terapia endocrino-chirurgica. In: Casa (ed) I tumori della mammella. Ambrosiana, Milano, p 289Google Scholar
  7. 7.
    Dao TL, Nemoto T, Bross IDJ (1967) A controlled, randomized comparative study of early and late adrenalectomy in women with advanced mammary cancer. In: Forrest APM, Kunklers PB (eds) Prognostic factors in breast cancer. Livingstone, Edinburgh, p 177Google Scholar
  8. 8.
    Dargent M, Mayer M (1959) La transplantation surreno-splenique dans le traitment du cancer du sein en phase avancée. A propos de 24 cas. Mem Acad Chir 85: 112PubMedGoogle Scholar
  9. 9.
    De Sombre ER, Carbone PP, Jensen EV, Lipsett MB, McGuire WL, Wells SA, Witliff JL (1979) Steroid receptors in breast cancer. An NIH consensus development conference, 27–29 June, 1979Google Scholar
  10. 10.
    Diczfalusy E, Notterg G, Edsmyr F, Westman A (1959) Estrogen excretion in breast cancer patients before and after ovarian irradiation and oophorectomy. J Clin Endocrinol 19: 1230CrossRefGoogle Scholar
  11. 11.
    Fracchia AA, Farrow JH, De Palo AJ, Conolly DT, Huvos AG (1969) Castration for primary inoperable or recurrent breast carcinoma. Surg Gynecol Obstet 128: 1226PubMedGoogle Scholar
  12. 12.
    Gower DB (1974) Modifiers of steroid-hormone metabolism. A review of their chemistry, biochemistry and clinical applications. J Steroid Biochem 5: 501PubMedCrossRefGoogle Scholar
  13. 13.
    Hayward S (1970) Hormones and human breast cancer. Springer, Berlin Heidelberg New York (Recent results in cancer research, vol 24 )Google Scholar
  14. 14.
    Hardy J (1967) Hypophysectomie trans-sphenoidale. In: Dargent M, Romieu CL (eds) Major endocrine surgery for treatment of the cancer of the breast in advanced stages. Simep, Lyon, p 97Google Scholar
  15. 15.
    Hardy J, Ciric IS (1968) Selective anterior hypophysectomy in the treatment of diabetic retinopathy: a transphenoidal microsurgical technique. JAMA 203: 73PubMedCrossRefGoogle Scholar
  16. 16.
    Huggins C, Scott WW (1945) Bilateral adrenalectomy in prostatic cancer. Ann Surg 122: 1031CrossRefGoogle Scholar
  17. 17.
    Huggins C, Bergenstal DM (1952) Inhibition of human mammary and prostatic cancers by adrenalectomy. Cancer Res 12: 134PubMedGoogle Scholar
  18. 18.
    Hughes SWM, Burley DM (1970) Aminoglutethimide. A “side effect” turned to therapeutic advantage. Postgrad Med J 46: 409CrossRefGoogle Scholar
  19. 19.
    Juret P (1966) Endocrine surgery in human cancers. Thomas, SpringfieldGoogle Scholar
  20. 20.
    Kennedy BJ, Mielke PW Jr, Fortuny IE (1960) Therapeutic castration versus prophylactic castration and breast cancer. Surg Gynecol Obstet 118: 524Google Scholar
  21. 21.
    Luft R, Olivecrona H (1975) Hypophysectomy in management of neoplastic disease. Bull NY Acad Med 33: 5Google Scholar
  22. 22.
    Mayer M, Dargent M, Pommatau E, Leaz S (1967) Resultats de la transplantation surrenosplenique associée à la surrenalectomie droite et à l’ovariectomie. In: Dargent M, Romieu CI (eds) Major endocrine surgery for the treatment of cancer of the breast in advances staged. Simep Lyon, p 67Google Scholar
  23. 23.
    Pearson OH, Ray BS (1960) Hypophysectomy in the treatment of advanced cancer. Am J Surg 99: 544PubMedCrossRefGoogle Scholar
  24. 24.
    Philbert M, Laudaut MH, Bricaire LH (1966) Etude clinique et biologique d’un inibiteur de l’hormonosynthèse corticosurrénale: l’aminoglutethimide. Ann Endocrinol 29: 189Google Scholar
  25. 25.
    Rand RW, Dashe AM, Paglia DE, Conway LW, Solomon DH (1964) Stereotactic cryohypo- physectomy. JAMA 189: 255PubMedCrossRefGoogle Scholar
  26. 26.
    Ruffo A, Badellino F, Rossotto P et al. (1960) Il trattamento endocrino-chirurgico dei tumori maligni. Omnia Therapeutica, vol XI, genn.-marzoGoogle Scholar
  27. 27.
    Santen RJ, Lipton A, Kendall J (1974) Successful medical adrenalectomy with aminoglute-thimide. Role of altered drug metabolism. JAMA 230: 1661PubMedCrossRefGoogle Scholar
  28. 28.
    Santen RJ, Wells SA Jr (1980) The use of aminoglutethimide in the treatment of patients with metastatic carcinoma of the breast. Cancer 46: 1066PubMedCrossRefGoogle Scholar
  29. 29.
    Schweitzer RJ (1980) Oophorectomy-adrenalectomy. Cancer 46: 1061PubMedCrossRefGoogle Scholar
  30. 30.
    Sirtori C, Pizzetti F, Catania VC (1958) Studio istologico e istochimico dei surreni e delle ovaie in pazienti portatrici di carcinoma mammario. Tumori 44: 263PubMedGoogle Scholar
  31. 31.
    Treves N, Finkbeiner JA (1958) An evaluation of therapeutic surgical castration in the treatment of metastatic recurrent and primary inoperable mammary carcinoma in women. An analysis of 191 patients. Cancer 11: 421PubMedCrossRefGoogle Scholar
  32. 32.
    Veronesi U, Pizzocaro G (1962) Oophorectomy for advanced carcinoma of the breast. Surg Gynecol Obstet 115: 443Google Scholar
  33. 33.
    Veronesi U, Pizzocaro G (1966) L’ovariectomia nella terapia del carcinoma avanzato della mammella. Tumori 52: 465PubMedGoogle Scholar
  34. 34.
    Weick JK, Cooperman AM (1978) Ovarian suppression and breast cancer. Surg Clin North Am 58: 795PubMedGoogle Scholar
  35. 35.
    Zervas NT (1969) Stereotaxic radiofrequency surgery of the normal and abnormal pituitary gland. N Engl J Med 280: 429PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1984

Authors and Affiliations

  • F. Badellino
    • 1
  • G. Canavese
    • 1
  • G. Margarino
    • 1
  1. 1.Istituto Scientifico per lo Studio e la Cura dei Tumori, Istituto di oncologia sperimentale e clinica dell universitàIstituto Nazionale per la Ricerca sul caucroGenovaItaly

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