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British Interlaboratory Quality Assessment of Steroid Receptor Assays

  • S. Cowan
  • R. E. Leake
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 91)

Abstract

Interlaboratory quality assessment of steroid receptor assays began in 1977 with a small study initiated through the Christie Hospital, Manchester (Dr. D. Barnes). This study was extended to include nine laboratories in 1979, since when each laboratory has participated regularly (see Part VII). With centres in Birmingham (Dr. A. Hughes), Cardiff (Drs. R. Nicholson and D. Wilson), Edinburgh (Dr. A. Hawkins), Glasgow (Dr. R. Leake), London (Drs. H. Braunsberg, R. King and A. Wilson) and Manchester (Drs. D. Barnes and A. Howell), the country is reasonably well covered, although additional groups continue to show an interest in the study. We are also fortunate to have an additional control through the participation of the Nijmegen group.

Keywords

Oestrogen Receptor Scatchard Plot Receptor Concentration Quality Assessment Study Human Myometrium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248–254PubMedCrossRefGoogle Scholar
  2. 2.
    Hawkins RA, Roberts MM, Forest APM (1980) Oestrogen receptors and breast cancer: current status. Br J Surg 67: 153–169PubMedCrossRefGoogle Scholar
  3. 3.
    Leake RE, Laing L, Smith DC (1979) A role for nuclear oestrogen receptors in prediction of therapy regime for breast cancer patients. In: King RJB (ed) Steroid receptor assays in human breast tumours: methodological and clinical aspects. Alpha Omega, Cardiff, pp 73–85Google Scholar
  4. 4.
    Silversward C, Skoog L, Humla S, Gustafsson SA, Nordenskjold B (1980) Intratumoral variation of cytoplasmic and nuclear oestrogen receptor concentrations in human mammary carcinoma. Eur J Cancer 16: 59–65CrossRefGoogle Scholar
  5. 5.
    Tilley WD, Keightley DD, Cant LM (1978) Inter-site variation of oestrogen receptors in human breast cancer. Br J Cancer 38: 544–546PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1984

Authors and Affiliations

  • S. Cowan
    • 1
  • R. E. Leake
    • 1
  1. 1.Department of BiochemistryUniversity of GlasgowGlasgowUK

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