Arterial Infusion Chemotherapy for Hepatic Metastases

  • J. Pettavel
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 86)


In the treatment of primary and secondary liver cancer, the respective roles of surgery and chemotherapy are far from being established. Surgical treatment by itself is preferred for primary hepatic tumors, bulky solitary metastases, and smaller hepatic metastases limited to one lobe (Pettavel and Meyer 1979). In addition, the excision of one or even several metastases is generally preferable before instituting chemotherapy. The logical basis for arterial chemotherapy as treatment for liver metastases has been described elsewhere (Pettavel and Morgenthaler 1970). There is a considerable choice of methods, associated with different adjuvant means: mono- or polychemotherapy, continuous or intermittent injections, simultaneous or sequential chemotherapy. All these can be used alone or in association with some form of hepatic ischemia: complete liver dearterialization, ligation of one or all main liver arteries, temporary occlusion of the hepatic artery (Bengmark and Fredlund 1978), and eventually some form of arterial embolization.


Hepatic Artery Hepatic Metastasis Infusion Chemotherapy Hepatic Arterial Infusion Hepatic Arterial Infusion Chemotherapy 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1983

Authors and Affiliations

  • J. Pettavel
    • 1
  1. 1.Department of SurgeryUniversity of Lausanne Medical School CenterLausanneSwitzerland

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