Abstract
Biological receptors are macromolecules which form strong and highly selective complexes with their substrates. Starting from a linear, formally one-dimensional, primary structure, they fold up into a tertiary structure, maintained mainly by noncovalent interactions, which delineates three-dimensional crevices and cavities, whose size, shape, and binding sites are complementary to those of the substrate.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Lehn JM (1973) Struct Bonding Berlin 16: 1
Lehn JM (1978) Acc Chem Res 11: 49; (1978) Pure Appi Chem 50: 871
Lehn JM (1980) Leçon Inaugurale au College France, Paris
Ovchinnikov Yu A, Ivanov VT, Shkrok AM (1974) Membrane active complexones, BBA Library, vol XII. Elsevier, Amsterdam
Pedersen, CJ, Frensdorff HK (1972) Angew Chem 84: 16
Cram DJ, Cram JM (1978) Acc Chem Res 11: 8
Graf E, Kintzinger JP, Lehn JM, to be published
Stoddart JF (1979) Chem Soc Rev 8: 85
Jong de F, Reinhoudt DN (1980) In: Gold V, Bethell D (eds) Advances in physical organic chemistry, vol XVII. Academic Press, London New York, p 279
Behr JP (1980) In: Braibanti A (ed) Bioenergetics and thermodynamics: Model systems. D Reidei, Boston, p 425
Behr JP, Lehn JM (1980) Helv Chim Acta 63: 2112
Kotzyba-Hibert F, Lehn JM, Vierling P (1980) Tetrahedon Lett 21: 941
Kintzinger JP, Kotzyba-Hibert F, Lehn JM, Pagelot A, to be published
Behr JP, Lehn JM (1976) J Am Chem Soc 98: 1743
Trainor GL, Breslow R (1981) J Am Chem Soc 103: 154 and references therein; Saenger W (1980) Angew Chem Int Ed Engl 19: 344
Murakami Y, Aoyama Y, Dobashi K (1977) J Chem Soc Perkin Trans 2, 24 and 32, and references therein
Chao Y, Cram DJ (1976) J Am Chem Soc 98: 1015; Bergen van TJ, Kellogg RM (1977) J Am Chem Soc 99: 3882
Behr JP, Lehn JM (1978) J Chem Soc Chem Commun: 143
Lehn JM, Sirlin C (1978) J Chem Soc Chem Commun: 949
Lehn JM (1979) Pure Appi Chem 51: 979
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Behr, J.P., Lehn, J.M. (1981). Design of Synthetic Molecular Receptors and Catalysts. In: Eggerer, H., Huber, R. (eds) Structural and Functional Aspects of Enzyme Catalysis. Colloquium der Gesellschaft für Biologische Chemie 23.–25. April 1981 in Mosbach/Baden, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81738-0_3
Download citation
DOI: https://doi.org/10.1007/978-3-642-81738-0_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81740-3
Online ISBN: 978-3-642-81738-0
eBook Packages: Springer Book Archive