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Effektorzellen der anaphylaktischen Reaktion

  • Conference paper
XXXII. Tagung gehalten in Westerland/Sylt vom 16. bis 20. September 1980

Part of the book series: Verhandlungen der Deutschen Dermatologischen Gesellschaft ((VDGDERMATOLOGIE,volume 32))

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Zusammenfassung

Während Makrophagen und T- und B-Lymphozyten für die Stimulierung und Regulierung der IgE-spezifischen Immunreaktion verantwortlich sind, fällt die eigentliche Effektorfunktion im akuten allergischen Geschehen der Gewebemastzelle und dem dieser Zelle sehr ähnlichen Blutbasophilen zu. Beide Zellen können innerhalb von Sekunden nach einer spezifischen Stimulierung verschiedene Vermittlersubstanzen freilassen, worauf es lokal oder im gesamten Organismus zu massiven Veränderungen kommt. Durch Einwirken dieser primären Mediatoren können weitere Effektorzellen, hauptsächlich eosinophile und neutrophile Zellen, zu Hilfe gerufen werden und den Ablauf der Entzündungsreaktionen durch Mediatoren und modulierende Substanzen entscheidend verändern. Diese Zellen und die komplexen Vorgänge, die durch sie verursacht werden, sollen hier anhand neuerer Befunde diskutiert werden, um auf diese Weise den klinischen Ablauf der akuten allergischen Reaktion verständlicher werden zu lassen.

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Authors and Affiliations

  1. Universitäts-Hautklinik, von Esmarchstr. 56, D-4400, Münster, Deutschland

    B. M. Czarnetzki

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  1. B. M. Czarnetzki
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Editors and Affiliations

  1. Universitäts-Hautklinik, Schittenhelmstraße 7, D-2300, Kiel, Deutschland

    E. Christophers (Tagungsleiter) & M. Goos (Tagungssekretär) (Tagungsleiter) &  (Tagungssekretär)

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© 1981 Springer-Verlag Berlin Heidelberg

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Czarnetzki, B.M. (1981). Effektorzellen der anaphylaktischen Reaktion. In: Christophers, E., Goos, M. (eds) XXXII. Tagung gehalten in Westerland/Sylt vom 16. bis 20. September 1980. Verhandlungen der Deutschen Dermatologischen Gesellschaft, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81671-0_27

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  • DOI: https://doi.org/10.1007/978-3-642-81671-0_27

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-10909-9

  • Online ISBN: 978-3-642-81671-0

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