Hair Research pp 330-335 | Cite as

Antiandrogens — Basic Concepts for Treatment

  • J. Hammerstein

Abstract

Hirsutismus and androgenetic alopecia have several characteristics in common:
  • Both hair disorders are generally believed to be androgen-mediated by an increase in either systemic androgen production or androgen sensitivity of the target organ.

  • In both cases a male-type hair pattern is predominant, i.e. an increase in terminal body hair with a predilection to the male body areas or a decrease in scalp hair ultimately leading to baldness.

  • Both hair disturbances are suitable for hormone treatment, especially with antiandrogens.

  • Last not least, medical care of these disorders requires both dermatological and endocrinological expertise. A close cooperation between the two medical specialities is of benefit to the patient.

Keywords

Estrogen Testosterone Androgen Estradiol Valerate 

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References

  1. Hammerstein J (1979a) Antiandrogens. Clinical aspects in hair diseases. In: Orfanos CE (ed) Hair and hair diseases. Fischer, Stuttgart New YorkGoogle Scholar
  2. Hammerstein J (1979b) Möglichkeiten und Grenzen der endokrinen Therapie. Proceedings of the „Symposium über Androgenisierungserscheinungen bei der Frau“. Excerpta Medica, Amsterdam Oxford PrincetonGoogle Scholar
  3. Hammerstein J, Cupceancu B (1969) Behandlung des Hirsutismus mit Cyproteronacetat. Dtsch Med Wochenschr 94:829PubMedCrossRefGoogle Scholar
  4. Hammerstein J, Meckies J, Leo-Roßberg I, Moltz L, Zielske F (1975) Use of cyproterone acetate(CPA) in the treatment of acne, hirsutism and virilism. J Steroid Biochem 6:827PubMedCrossRefGoogle Scholar
  5. Lachnit-Fixson U, Kaufmann J (1977) Zur Beeinflussung von Androgenisierungserscheinungen - Doppelblindstudie eines cyproteronacetathaltigen Präparats (SHB 209 AB) gegen Neogynon. Med Klin 72:1922PubMedGoogle Scholar
  6. Moltz L, Meckies J, Hammerstein J (1979) Niedrig dosierte Cyproteronacetat/Östrogentherapie bei Frauen mit Androgenisierungserscheinungen. Dtsch Med Wochenschr (in press)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1981

Authors and Affiliations

  • J. Hammerstein
    • 1
    • 2
  1. 1.Division of Gynecological Endocrinology, Sterility and Family Planning, Department of Gynecology and ObstetricsUniversity Medical Center SteglitzBerlinWest-Germany
  2. 2.The Free University of BerlinBerlinWest-Germany

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