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General Principles of Immunology (as Related to Auto-immune Disease)

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Book cover Auto-immunity in the Endocrine System

Part of the book series: Monographs on Endocrinology ((ENDOCRINOLOGY,volume 20))

Abstract

The term “immunity” may be defined as those physiological mechanisms which endow the organism with the capacity to recognize substances as foreign, and to neutralize, eliminate or metabolize them without injury to its own tissues. Responses to such foreign substances may be divided into two types, i.e. those which are non-specific, and those which are specific immunological responses. Non-specific responses may occur following the initial and even subsequent exposure to foreign antigen, and are not dependent on specific recognition. A non-specific response involves the participation of cellular and chemical mediators, such as macrophages, lysozymes, properdin, interferon, prostaglandins and complement (Playfair 1975).

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Authors and Affiliations

  1. Department of Medicine, University of Toronto, M4Y 1J3, Toronto, Ontario, Canada

    Robert Volpé M.D., F.R.C.P.(C), F.A.C.P. (Professor, Physician-in-Chief)

  2. The Wellesley Hospital, M4Y 1J3, Toronto, Ontario, Canada

    Robert Volpé M.D., F.R.C.P.(C), F.A.C.P. (Professor, Physician-in-Chief)

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  1. Robert Volpé M.D., F.R.C.P.(C), F.A.C.P.
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© 1981 Springer-Verlag Berlin, Heidelberg

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Volpé, R. (1981). General Principles of Immunology (as Related to Auto-immune Disease). In: Auto-immunity in the Endocrine System. Monographs on Endocrinology, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81624-6_1

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  • DOI: https://doi.org/10.1007/978-3-642-81624-6_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81626-0

  • Online ISBN: 978-3-642-81624-6

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