Summary
Histochemical and immunohistological examinations were carried out at different stages of thiamine-deficient encephalopathy in rats. The respiratory enzymatic activity decreased in the most damaged area correlating well with the neuropathological findings. There was an inverse relationship between the damaged area and its marginal zone; the latter showed an increase of the same enzymatic activity. The capillary network and the activity of the vessel walls seemed to be almost unimpaired. The immunohistological investigations showed only a moderate extravasation of the plasma proteins.
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References
Ibrahim MZ, Pascoe E, Alam S, Miquel J (1970) Glycogen and Phosphorylase activity in rat brain during recovery from several forms of hypoxia. Am J Pathol 63:403–416
Mossakowski M, Long DM, Myers RE, Rodriquez de Curet H, Klatzo I (1968) Early histochemical changes in perinatal asphyxia. J Neuropathol Exp Neurol 27:500–516
Mrsulja B, Spatz M, Walker JT, Klatzo I (1979) Histochemical investigations of the Mongolian Gerbil’s brain during unilateral ischemia. Acta Neuropathol (Berl) 46:123–131
Robertson MD, Manz HJ (1971) Effect of thiamine deficiency on the competence of the blood-brain barrier to albumin labeled with fluorescent dyes. Am J Pathol 63:393–402
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© 1981 Springer-Verlag
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Takáts, A., Komoly, S., Fazekas, A., Tárczy, M., Papp, M., Auguszt, A. (1981). Comparative Histochemical and Immunofluorescent Observations in Thiamine Deficient Encephalopathies. In: Jellinger, K., Gullotta, F., Mossakowski, M. (eds) Experimental and Clinical Neuropathology. Acta Neuropathologica Supplementum, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81553-9_15
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DOI: https://doi.org/10.1007/978-3-642-81553-9_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-10449-0
Online ISBN: 978-3-642-81553-9
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