Abstract
The immune status of the tumor-bearing patient remains poorly defined. In various solid-tumor-bearing patients, we demonstrated the absence of ADCC modifications in the patient in relapse or in evolution. These same patients presented a significant increase in immune complexes when compared with patients in remission. Furthermore, we noted a decreased NK activity, a decreased number of ARFC, corresponding to a helper T cell subpopulation, and a corollary increase in T-dependent suppressor activity. These results, on the whole, suggest an immune imbalance and that the helper cell — suppressor cell ratio should be investigated in greater depth within the context of the immune response in the cancer patient.
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Serrou, B., Gauci, L., Caraux, J., Cupissol, D., Thierry, C., Esteve, C. (1980). Immune Imbalance in Cancer Patients. In: Mathé, G., Muggia, F.M. (eds) Cancer Chemo- and Immunopharmacology. Recent Results in Cancer Research, vol 75. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81491-4_7
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DOI: https://doi.org/10.1007/978-3-642-81491-4_7
Publisher Name: Springer, Berlin, Heidelberg
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