Abstract
A short review is presented of animal models used in cancer immunotherapy. Attention is focused on spontaneous canine tumors submitted to active immunotherapy after surgery, and on the use of immunorestoring agents to prevent spontaneous tumors in age-immunodepressed mice.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Bekesi JG, Holland JF (1974) Combined chemotherapy and immunotherapy of transplantable and spontaneous murine leukemia in DBA/2 and AkR mice. Recent Results Cancer Res 47:357–369
Bonadonna G, Mathé G, Salmon SE (eds) (1979) Adjuvant therapies and markers of post-surgical minimal residual disease. II. Adjuvant therapies and markers of the various primary tumors. Recent Results Cancer Res 68
Bruley-Rosset M, Florentin I, Kiger N, Davigny M, Mathé G (1978) Effects of bacillus Calmette-Guérin and levamisole on immune responses in young adult and age-immuno-depressed mice. Cancer Treat Rep 62:1641–1650
Bruley-Rosset M, Florentin I, Kiger N, Schulz J, Davigny M, Mathé G (1980) Age-related changes of the immune response and immunorestoration by stimulating agents. In: Doria G, Eshkol A (eds) The immune system, function and therapy of dysfunction. Academic Press, New York, pp 171–187
Bruley-Rosset M, Florentin I, Kiger N, Schulz J, Mathé G (1979) Restoration of impaired immune functions of aged animals by chronic bestatin treatment. Immunology 38:75–83
Coid CR (1978) Selection of animals suitable for biomedical investigations. J Soc Med 71:675–677
Fortner JG (1977) Management of recurrent malignant melanoma. In: Third International Symposium on Oncology, Teheran 4–8 March, p 60 (abstr 21)
Huchet R, Lhéritier J (1976) Non-specific immunodepression induced by tumor-cell extracts. Recent Results Cancer Res 56:65–71
International Meeting on Comparative Therapeutic Trials, Paris, January 1978. In: Lortat-Jacob JL, Mathé G, Servier J (eds). Biomedicine 28 (special issue)
Kennel SJ, Tsakeres F, Kelly PA, Allison DP (1978) Defective C-type retrovirus particles secreted by L1210 leukemia cells. Cancer Res 38:4574–4579
Lacour F, Delage G, Chianale C (1975) Reduced incidence of spontaneous mammary tumors in C3H/He mice after treatment with polyadenylate-polyuridylate. Science 187:256–257
Lemonde P (1974) Inhibition de la néoplasie par stimulation de l’immunité. Aspects expérimentaux. Union Med Can 103:1716–1728
Mathé G (1976) Cancer active immunotherapy: Immunoprophylaxis and immunorestoration. An introduction. Recent Results Cancer Res 55
Mathé G (1978) Systemic active immunotherapy is shifting from the middle ages to a renaissance period. I. The multiplication of randomized trials showing significant effect of active immunotherapy on residual minimal disease. Cancer Immunol Immunother 5:149–152
Mathé G, Halle-Pannenko I. Bourut C (1973) Active immunotherapy in spontaneous leukemia of AkR mice. Exp Hematol 1:110–114
Milas L, Hunter N, Basic I, Rodney Withers H (1974) Complete regressions of an established murine fibrosarcoma induced by systemic application of Corynebacterium granulosum. Cancer Res 34:2470–2475
Nathrath WBJ (1978) Organ and tumour antigens in malignant disease: A review. J R Soc Med 71:755–671
Nicolson GL (1979) Cancer metastasis. Sci Am 240:50–60
Owen LN, Bostock DE (1974) Effects of intravenous BCG in normal dogs, and dogs with spontaneous osteosarcoma. Eur J Cancer 10:775–780
Owen LN, Bostock DE, Lavelle RB (1977) Studies on therapy of osteosarcoma in dogs using BCG vaccine. J Am Vet Radiol Soc 18:27–29
Piessens WF, Lachapelle FL, Legros N, Heuson JC (1970) Facilitation of rat mammary tumour growth by BCG. Nature 228:1210–1211
Renoux G, Kassel RL, Renoux M, Fiore NC, Guillamin JM, Palat A (1977) Immunomodulation by levamisole in normal and leukemic mice: Evidence for a serum transfer. In: Chingos MA (ed) Immunomodulation of host immune resistance in the prevention or treatment of induced neoplasias. U.S. Government Printing Office, Washington, pp 45–51
Salmon SS, Jones SE (eds) (1979) Adjuvant therapy of cancer. Grune and Stratton, New York
Terry WD, Windhorst D (eds) (1978) Immunotherapy of cancer: Present status of trials in man. Raven, New York
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1980 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Mathé, G., Florentin, I., Bruley-Rosset, M., Kiger, N. (1980). Progress in Experimental Systemic Active Immunotherapy of Cancer. In: Mathé, G., Muggia, F.M. (eds) Cancer Chemo- and Immunopharmacology. Recent Results in Cancer Research, vol 75. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81491-4_3
Download citation
DOI: https://doi.org/10.1007/978-3-642-81491-4_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81493-8
Online ISBN: 978-3-642-81491-4
eBook Packages: Springer Book Archive