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Endocrine Treatment of Breast Cancer pp 30–44Cite as

Anti-Oestrogen Action in Experimental Breast Cancer

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Abstract

The pharmacological response to a drug is dependent upon efficient absorption after administration, followed by distribution to the site of action. The duration of the pharmacological effect is directly related to the biological half-life of the parent drug and its active metabolites. At the molecular level, the tissue response is the result of an interaction of the drug and its metabolites with a biochemical target or receptor.

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Author information

Authors and Affiliations

  1. Department of Pharmacology, Medical and Dental Building, University of Leeds, Leeds, LS2 9JT, UK

    V. C. Jordan, K. E. Naylor, C. J. Dix & G. Prestwich

Authors
  1. V. C. Jordan
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  2. K. E. Naylor
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  3. C. J. Dix
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  4. G. Prestwich
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Editor information

Editors and Affiliations

  1. Chirurgische Klinik, Klinikum der Universität Heidelberg, Kirschnerstraße 1, D-6900, Heidelberg 1, Germany

    B. Henningsen  & F. Linder  & 

  2. ICI-Pharma, Clinical Research, Postfach 103109, D-6900, Heidelberg 1, Germany

    C. Steichele

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© 1980 Springer-Verlag Berlin Heidelberg

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Jordan, V.C., Naylor, K.E., Dix, C.J., Prestwich, G. (1980). Anti-Oestrogen Action in Experimental Breast Cancer. In: Henningsen, B., Linder, F., Steichele, C. (eds) Endocrine Treatment of Breast Cancer. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 71. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81406-8_8

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  • DOI: https://doi.org/10.1007/978-3-642-81406-8_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81408-2

  • Online ISBN: 978-3-642-81406-8

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