Abstract
Clinical studies of drugs in the treatment of cancer have been divided into three parts: Phase I is a pharmacologic study in which the limiting side effects, a satisfactory route of administration, and dose schedule are determined. Phase II is the screening in a broad spectrum of tumor types for evidence of a minimal degree of antitumor activity. Phase III is a trial to determine the degree of antitumor activity in one (or more) specific tumor type; it is usually comparative in that a control group is included.
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© 1980 Springer-Verlag Berlin Heidelberg
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Majima, H. (1980). Phase II Study of Antineoplastic Agents in Japan. In: Carter, S.K., Sakurai, Y. (eds) New Anticancer Drugs. Recent Results in Cancer Research, vol 70. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81392-4_6
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DOI: https://doi.org/10.1007/978-3-642-81392-4_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81394-8
Online ISBN: 978-3-642-81392-4
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