Abstract
Razoxane (ICRF 159) is an antimitotic drug that was developed at the laboratories of the Imperial Cancer Research Fund, London, England. The drug is related to the chelating agent EDTA and was found to be active in a wide range of experimental tumours (Fig. 1). It blocks cell cycle progression in the pre-mitotic or early mitotic phases of the cell cycle.
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Gilbert, J.M., Cassell, P., Ellis, H., Wastell, C., Hermon-Taylor, J., Hellman, K. (1979). Adjuvant Treatment With Razoxane (ICRF 159) Following Resection of Cancer of the Stomach. In: Bonadonna, G., Mathé, G., Salmon, S.E. (eds) Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II. Recent Results in Cancer Research, vol 68. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81332-0_33
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DOI: https://doi.org/10.1007/978-3-642-81332-0_33
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