Chemotherapy in Non-Hodgkin’s Malignant Lymphomas According to Potential Evolutive Groups

  • J. J. Sotto
  • M. Michallet
  • M. F. Sotto
  • B. Lachet
  • H. Martin
  • R. Schaerer
  • C. Vrousos
  • D. Hollard
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 65)


Histology and cytology show us the strong heterogeneity of non-Hodgkin’s malignant lymphomas (NHML). Numerous classifications have been proposed. They contain 6–12 classes [18, 25] which more or less match [5, 9, 10, 12, 17, 18, 20, 25]. If, with luck, a nonsophisticated and reproducible classification could predict the evolution, we would have to take it into account and suit the treatment to it. Nevertheless, none of the present classification systems are able to solve the problem for all the patients with NHML. The aim of a practical classification is to clearly distinguish the morphologic groups with the same predictable evolution possibly to cancel those in which the prognosis is still confused. Such well-defined groups have already been described, e.g., African Burkitt’s lymphoma [1], immunoblastic sarcoma [19], convoluted cell lymphosarcoma [18, 30], nodular well-differentiated lymphomas [4, 16], and histiocytosarcoma [22]. Nevertheless, it is still difficult to compare the potential evolution of the morphologic groups from one center to another. There are several causes: the reproducibility is not easy, the treatments are different, and even the frontiers of the disease are badly separated from the chronic lymphocytic leukemia or the acute leukemia.


Complete Remission Chronic Lymphocytic Leukemia Acute Leukemia Malignant Lymphoma Cytosine Arabinoside 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1978

Authors and Affiliations

  • J. J. Sotto
  • M. Michallet
  • M. F. Sotto
  • B. Lachet
  • H. Martin
  • R. Schaerer
  • C. Vrousos
  • D. Hollard

There are no affiliations available

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