Abstract
In 1956, Castleman studied a group of patients with “asymptomatic, large, benign hyperplastic mediastinal lymph nodes that resembled thymomas” [3]. Although a similar lesion was subsequently described by others under various designations including lymph nodal hamartoma [1], angiofollicular mediastinal lymph node hyperplasia [7], and benign lymphoid mass of probable hamartomatous nature [10], this disorder is referred to in many countries as “Castleman’s disease.” The lesion has a predilection for the mediastinum, but has been described at other sites, usually involving lymph nodes, although on occasion in extranodal locations [4]. The latter observation has provided support for the theory that the lesion represents a lymphoid hamartoma [10].
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Dorfman, R.F., Cibull, M. (1978). Castleman’s Disease. In: Mathé, G., Seligmann, M., Tubiana, M. (eds) Lymphoid Neoplasias I. Recent Results in Cancer Research, vol 64. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81246-0_34
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DOI: https://doi.org/10.1007/978-3-642-81246-0_34
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