Effect of Direct Current on the Healing of Fractures

  • S. Stan
  • J. C. Mulier
  • W. Sansen
  • P. De Waele


Artificial stimulation of osteogenesis and subsequent acceleration of the healing of fractures has always been an exciting prospect. Thus far, no direct method of control over the healing or growth of bone exists. The concept of stimulating electrically the formation of new bone appears to be the logical consequence of the presence of physiologic electric currents in living bone. These currents represent a part of a control system that takes part in the growth and remodeling of bone and also on the healing of fractures.


Alternate Current Medullary Canal Medullary Cavity Exciting Prospect Pulse Direct Current 
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  1. 1.
    Bassett, C.A.L.: Electromechanical factors regulating bone architecture. Third European Symposium on Calcified Tissues. Fleisch, H., Blackwood, H.J.J., Owen, M. (eds.). Berlin: Springer-Verlag 1966, pp. 78–89Google Scholar
  2. 2.
    Becker, R.O., Bassett, C.A.L.: Generation of electrical potentials by bone in response to mechanical stress. Science 137, 1063–1064 (1962)PubMedCrossRefGoogle Scholar
  3. 3.
    Cochran, G.V.B., Pawluk, R.J., Bassett, C.A.L.: Electromechanical characteristics of bone under physiologic moisture conditions, Clin. Orthop. 58, 249–270 (1968)PubMedGoogle Scholar
  4. 4.
    Friedenberg, Z.B., Roberts, P.G., Didizian, N.H., Brighton, C.T.: Stimulation of fracture healing by direct current in the rabbit fibula. J. Bone Joint Surg. 53A (7), 1400–1408 (1971)PubMedGoogle Scholar
  5. 5.
    Jorgensen, T.E.: The effect of electrical current on the healing time of crural fractures. Acta Orthop. Scand. 43, 421–437 (1972)PubMedCrossRefGoogle Scholar
  6. 6.
    Lavine, L.S., Lustrin, I., Shamos, M., Rinaldi, R., Liboff, Z.: Electrical enhancement of bone healing. Science 175, 1118–1121 (1972)CrossRefGoogle Scholar
  7. 7.
    Pilla, A.A.: Electrochemical information and energy transfer in vivo. J. Am. Chem. Soc. 761–767 (1972)Google Scholar
  8. 8.
    Richez, J., Chamay, A., Bieler, L.: Bone changes due to pulses of direct electric microcurrent, Virchows Arch. [Pathol. Anat.] 357, 11–18 (1972)CrossRefGoogle Scholar
  9. 9.
    Stan, S.: The influence of the electric current on bone regeneration. Belg. Veren. voor Orthop., Pellenberg, June 1975Google Scholar
  10. 10.
    Stan, S., Sansen, W., Stuyck, J., Mulier, J.: Comparison between the electrical behaviour of normal bone and that following in the healing of the fractures. Symposium on the Electrical Enhancement of the Bone, XIII SICOT, Copenhagen, 1975Google Scholar
  11. 11.
    Sansen, W., Dedijker, F., Stan, S., Mulier, J.: The four-point probe measurement of the impedance of bone in vivo. First European Symposium on Electrical Stimulation of Bone Growth and Repair, Brussels, 20 May, 1976Google Scholar
  12. 12.
    Stan, S., Sansen, W., Mulier, J.: Experimental study on the electrical impedance of the bone and the effect of direct current on the healing of the fractures. Clin. Orthop. 120, 264–267 (1976).Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • S. Stan
  • J. C. Mulier
  • W. Sansen
  • P. De Waele

There are no affiliations available

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