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Elektronische Datenverarbeitung

a) Data Processing in Dynamic Function Analysis

  • Chapter
Nuklearmedizin / Nuclear Medicine

Part of the book series: Handbuch der medizinischen Radiologie / Encyclopedia of Medical Radiology ((1523,volume 15 / 1 / A))

Abstract

Dynamic function measurements are performed in order to gain insight into physiological processes. Several conditions have to be met in order for measurements to yield the desired results:

  1. 1.

    The measurement itself must not alter the process to be measured. Radioactive tracers are ideally suited for this purpose: they are identical in chemical and physical characteristics with the cold substance, they are negligible in quantity, and they can be measured in a noninvasive manner. As a matter of fact, for most physiological tests, it is necessary to add sufficient cold substance in order to assure a realistic organ function.

  2. 2.

    The substance should be function-specific. Much progress has been made toward identifying and supplying radiopharmaceuticals with such organ and/or function specificity. While this specificity is presumed to be established for clinical investigations, it is exactly the object of other research-oriented measurements.

  3. 3.

    The substances should have a suitable detection characteristic. This refers both to the physicial qualifications, such as half-life, freedom of particular radiation, suitable energy spectrum, as well as chemical characteristics such as stability, purity, etc.

  4. 4.

    The radiopharmaceutical should imply low body burden when used as intended.

  5. 5.

    The radiopharmaceutical should be readily available and of guaranteed quality. Only if the commercial supply is secured, and the cost justifiable, will widespread application establish its usefulness.

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  1. R. Hindel
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  2. V. Klement
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  1. Abteilung für Nuklearmedizin und spezielle Biophysik, Medizinische Hochschule Hannover, Karl-Wiechert-Allee 9, D-3000, Hannover 61, Deutschland

    H. Hundeshagen

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© 1980 Springer-Verlag Berlin · Heidelberg

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Hindel, R., Klement, V. (1980). Elektronische Datenverarbeitung. In: Hundeshagen, H. (eds) Nuklearmedizin / Nuclear Medicine. Handbuch der medizinischen Radiologie / Encyclopedia of Medical Radiology, vol 15 / 1 / A. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81186-9_10

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  • DOI: https://doi.org/10.1007/978-3-642-81186-9_10

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  • Online ISBN: 978-3-642-81186-9

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