Summary, Applications of these Data, and Perspectives for the Future

  • Bruce S. Schoenberg
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 58)


Results for non-simultaneously diagnosed malignant tumors from Connecticut indicate that individuals with one malignant neoplasm have 1.29 times the risk of developing a new independent primary tumor when compared to individuals who never had cancer (P < 0.01). However, the increased risk of multiple primary tumors is highly selective on a site-specific basis. Table 135 presents Connecticut Registry data indicating the risk of a subsequent primary malignancy by anatomic site of the later primary in patients with a first primary cancer. Tables 136 and 137 present tabulations for anatomic sites with statistically significant excesses and deficiencies, with an analysis by time interval between the two malignancies. Finally, Table 138 presents figures showing histologic confirmation for site-group pairs with significant excesses of observed-over-expected later primary malignant neoplasms.


Anatomic Site Significant Excess Primary Malignant Neoplasm Multiple Primary Cancer Multiple Primary Tumor 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1977

Authors and Affiliations

  • Bruce S. Schoenberg
    • 1
    • 2
    • 3
    • 4
  1. 1.Department of Medical Statistics and Epidemiology and Department of NeurologyMayo ClinicRochesterUSA
  2. 2.National Cancer InstituteUSA
  3. 3.Department of Epidemiology and Public HealthYale University School of MedicineUSA
  4. 4.Department of NeurologyGeorgetown University School of MedicineUSA

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