Active Transport and the Maintenance of Transmembrane Ionic Distributions

  • Michael C. Mackey
Part of the Lecture Notes in Biomathematics book series (LNBM, volume 7)


In all the discussion to this point I have not considered the question of how biological cells are able to maintain asymmetric transmembrane ion concentrations. In most cells there is a high external and a low internal concentration of Na+; the situation is reversed for K+. Taking Na+ as an example, it would be expected to diffuse into a cell because of the concentration gradient. Further, there should be an influx of Na+ because of the membrane electric field. From simple thermodynamic concepts this process should continue until external and internal Na+ concentrations are equal.


Active Transport Coupling Ratio Squid Giant Axon Active Transport System Active Transport Mechanism 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin · Heidelberg 1975

Authors and Affiliations

  • Michael C. Mackey
    • 1
  1. 1.Department of PhysiologyMcGill UniversityMontrealCanada

Personalised recommendations